Role of interleukin-18 in host defense against disseminated Candida albicans infection.

Authors :: Stuyt, R.J.L.
Netea, M.G.
Verschueren, C.M.M.
Fantuzzi, G.
Dinarello, C.A.
Meer, J.W.M. van der
Kullberg, B.J.
Stuyt, R.J.L.
Netea, M.G.
Verschueren, C.M.M.
Fantuzzi, G.
Dinarello, C.A.
Meer, J.W.M. van der
Kullberg, B.J.
Source :: Infection and Immunity; 3284; 6; 0019-9567; 6; 70; ~Infection and Immunity~3284~6~~~0019-9567~6~70~~
Publication Year :: 2002
Abstract: Item does not contain fulltext<br />In mice injected intravenously with Candida albicans, administration of anti-interleukin-18 (IL-18) antibodies increased the yeast load in the kidneys. There was no effect on the organ load with Candida when gamma interferon (IFN-gamma)-deficient mice were treated with anti-IL-18 antibodies, suggesting that the protective effect of IL-18 is mediated through endogenous IFN-gamma.

Database :: OAIster
Journal :: Infection and Immunity; 3284; 6; 0019-9567; 6; 70; ~Infection and Immunity~3284~6~~~0019-9567~6~70~~
Publication Type :: Electronic Resource
Accession number :: edsoai.on1366703275
Document Type :: Electronic Resource

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