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Markers of AIDS associated virus in patients with end-stage renal failure treated by hemodialysis

Authors :
Goldman, Michel
Liesnard, Corinne
Vanherweghem, Jean-Louis
Dolle, Nicole
Toussaint, Charles
Sprecher-Goldberger, Suzanne
Cogniaux, Jacqueline
Thiry, Lise
Goldman, Michel
Liesnard, Corinne
Vanherweghem, Jean-Louis
Dolle, Nicole
Toussaint, Charles
Sprecher-Goldberger, Suzanne
Cogniaux, Jacqueline
Thiry, Lise
Source :
British medical journal (Clinical research ed.), 293
Publication Year :
1986

Abstract

Patients and members of staff from a haemodialysis unit were tested for markers of infection with human T cell lymphotropic virus type III (HTLV-III), the virus associated with the acquired immune deficiency syndrome (AIDS). An enzyme linked immunosorbent assay showed eight of 100 patients to have antibodies to HTLV-III. In five of these patients past or present infection with HTLV-III was confirmed by Western blot analysis or detection of HTLV-III antigens in lymphocyte cultures, or both. Investigation of other risk factors for AIDS showed that the putative source of HTLV-III was unrelated to dialysis in two patients whereas blood transfusion was the most likely cause of contamination in the others. No member of staff gave a positive result in the enzyme linked immunosorbent assay. Nosocomial transmission of HTLV-III seems unlikely if precautions similar to those recommended for the control of hepatitis B infection are applied.<br />Journal Article<br />Research Support, Non-U.S. Gov't<br />SCOPUS: ar.j<br />info:eu-repo/semantics/published

Details

Database :
OAIster
Journal :
British medical journal (Clinical research ed.), 293
Notes :
1 full-text file(s): application/pdf, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1363763111
Document Type :
Electronic Resource