PSA-vergelijkbaarheid:Standaardisatie of harmonisatie?

Authors :: Van Zelst, B. D.
Blijenberg, B. G.
Van Zelst, B. D.
Blijenberg, B. G.
Source :: Van Zelst , B D & Blijenberg , B G 2003 , ' PSA-vergelijkbaarheid : Standaardisatie of harmonisatie? ' , Nederlands Tijdschrift voor Klinische Chemie en Laboratoriumgeneeskunde , vol. 28 , no. 1 , pp. 26-32 .
Publication Year :: 2003
Abstract: Objective: Investigation of the application of WHO calibrators for PSA (WHO 96/670 and WHO 96/668) in relationship with new developments regarding PSA measurements. Methods: The PSA assays used were those for Access, Elecsys and ACS: 180. We used 200 clinically described samples (BPH and PCa). Results: Comparing the manufacturer's calibration procedure with the WHO calibrators, revealed for total PSA slopes of 1.22, 0.92 and 1.04 for Access, Elecsys and ACS: 180 respectively. For free PSA we found 1.28, 0.83 and 1.62. Measurement of these calibrators in combination with the measurement of the clinical samples indicated that the methods for total PSA may be assumed equimolar. Conclusion: We found a good comparibility for free and total PSA. However, good interchangability of results is still not possible, due to the lack of reference methods.

Database :: OAIster
Journal :: Van Zelst , B D & Blijenberg , B G 2003 , ' PSA-vergelijkbaarheid : Standaardisatie of harmonisatie? ' , Nederlands Tijdschrift voor Klinische Chemie en Laboratoriumgeneeskunde , vol. 28 , no. 1 , pp. 26-32 .
Notes :: application/pdf, Dutch
Publication Type :: Electronic Resource
Accession number :: edsoai.on1356652900
Document Type :: Electronic Resource