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Frailty and long-COVID: is COVID-19 responsible for a transition in frailty status among older adults who survived hospitalization for COVID-19?

Authors :
Ferrara, M
Zarcone, C
Tassistro, E
Rebora, P
Rossi, E
Luppi, F
Foti, G
Squillace, N
Lettino, M
Strepparava, M
Bonfanti, P
Bellelli, G
Ferrara, Maria Cristina
Zarcone, Cristina
Tassistro, Elena
Rebora, Paola
Rossi, Emanuela
Luppi, Fabrizio
Foti, Giuseppe
Squillace, Nicola
Lettino, Maddalena
Strepparava, Maria Grazia
Bonfanti, Paolo
Bellelli, Giuseppe
Ferrara, M
Zarcone, C
Tassistro, E
Rebora, P
Rossi, E
Luppi, F
Foti, G
Squillace, N
Lettino, M
Strepparava, M
Bonfanti, P
Bellelli, G
Ferrara, Maria Cristina
Zarcone, Cristina
Tassistro, Elena
Rebora, Paola
Rossi, Emanuela
Luppi, Fabrizio
Foti, Giuseppe
Squillace, Nicola
Lettino, Maddalena
Strepparava, Maria Grazia
Bonfanti, Paolo
Bellelli, Giuseppe
Publication Year :
2023

Abstract

Background: There is a paucity of knowledge about the effects of COronaVIrus Disease-19 (COVID-19) on long-term frailty development or progression over time. Aim: This study aims to assess transitions in frailty status in older adults who survived hospitalization for COVID-19. Methods: This is a longitudinal panel study. A multidisciplinary outpatient follow-up service was established since summer 2020, for the evaluation of individuals discharged alive, after hospitalization due to COVID-19. Frailty status was assessed in-hospital and at follow-up using the clinical frailty scale (CFS). Main patients’ characteristics, including health, functional, cognitive, and psychological status were collected. Results: A total of 177 patients aged 65 years and older were evaluated until June 2022. They were predominantly male, with a median age of 70 (Q1–Q3 67–75) years and a median body mass index of 27.5 (Q1–Q3 24.9–30.6) kg/m2 at hospital admission. The median follow-up time was 6.3 (Q1–Q3 3.7–10.9) months. Sixty-one patients (34.5%) scored worse at CFS follow-up compared to hospital admission, and twenty-two patients (12.4%) became frail. Discussion and conclusion: This study shows that one out of three older patients previously hospitalized for COVID-19 had an unfavorable transition in CFS score during a median follow-up of nearly 6 months. Specific interventions to prevent frailty development or progression should be considered for patients at risk. Further studies are required to confirm our findings.

Details

Database :
OAIster
Notes :
STAMPA, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1354526616
Document Type :
Electronic Resource