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Durability of Immune Responses After Boosting in Ad26.COV2.S-Primed Healthcare Workers
- Source :
- SWITCH Research Group , Sablerolles , R S G , Rietdijk , W J R , Goorhuis , A , Postma , D F , Visser , L G , Schmitz , K S , Geers , D , Bogers , S , van Haren , E , Koopmans , M P G , Dalm , V A S H , Kootstra , N A , Huckriede , A L W , Akkerman , R , Beukema , M , Lafeber , M , van Baarle , D , de Vries , R D , van der Kuy , P H M & GeurtsvanKessel , C H 2023 , ' Durability of Immune Responses After Boosting in Ad26.COV2.S-Primed Healthcare Workers ' , Clinical infectious diseases : an official publication of the Infectious Diseases Society of America , vol. 76 , no. 3 , ciac495 , pp. e533-e536 .
- Publication Year :
- 2023
-
Abstract
- The emergence of SARS-CoV-2 variants raised questions regarding the durability of immune responses after homologous or heterologous boosters after Ad26.COV2.S-priming. We found that SARS-CoV-2-specific binding antibodies, neutralizing antibodies, and T cells are detectable 5 months after boosting, although waning of antibodies and limited cross-reactivity with Omicron BA.1 was observed.
Details
- Database :
- OAIster
- Journal :
- SWITCH Research Group , Sablerolles , R S G , Rietdijk , W J R , Goorhuis , A , Postma , D F , Visser , L G , Schmitz , K S , Geers , D , Bogers , S , van Haren , E , Koopmans , M P G , Dalm , V A S H , Kootstra , N A , Huckriede , A L W , Akkerman , R , Beukema , M , Lafeber , M , van Baarle , D , de Vries , R D , van der Kuy , P H M & GeurtsvanKessel , C H 2023 , ' Durability of Immune Responses After Boosting in Ad26.COV2.S-Primed Healthcare Workers ' , Clinical infectious diseases : an official publication of the Infectious Diseases Society of America , vol. 76 , no. 3 , ciac495 , pp. e533-e536 .
- Notes :
- application/pdf, English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1352447645
- Document Type :
- Electronic Resource