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Comparative effectiveness of intracranial hypertension management guided by ventricular versus intraparenchymal pressure monitoring: a CENTER-TBI study
Authors :
Volovici, V Pisică, D Gravesteijn, B Dirven, C Steyerberg, E Ercole, A Stocchetti, N Nelson, D Menon, D Citerio, G van der Jagt, M Maas, A Haitsma, I Lingsma, H Åkerlund, C Amrein, K Andelic, N Andreassen, L Audibert, G Azouvi, P Azzolini, M Bartels, R Beer, R Bellander, B Benali, H Berardino, M Beretta, L Beqiri, E Blaabjerg, M Lund, S Brorsson, C Buki, A Cabeleira, M Caccioppola, A Calappi, E Calvi, M Cameron, P Lozano, G Castaño-León, A Cavallo, S Chevallard, G Chieregato, A Coburn, M Coles, J Cooper, J Correia, M Czeiter, E Czosnyka, M Dahyot-Fizelier, C Dark, P De Keyser, V Degos, V Corte, F Boogert, H Depreitere, B Dilvesi, D Dixit, A Dreier, J Dulière, G Ezer, E Fabricius, M Foks, K Frisvold, S Furmanov, A Galanaud, D Gantner, D Ghuysen, A Giga, L Golubovic, J Gomez, P Grossi, F Gupta, D Helseth, E Hutchinson, P Jankowski, S Johnson, F Karan, M Kolias, A Kondziella, D Koraropoulos, E Koskinen, L Kovács, N Kowark, A Lagares, A Laureys, S Ledoux, D Lejeune, A Lightfoot, R Manara, A Martino, C Maréchal, H Mattern, J Mcmahon, C Menovsky, T Misset, B Muraleedharan, V Murray, L Negru, A Newcombe, V Nyirádi, J Ortolano, F Payen, J Perlbarg, V Persona, P Piippo-Karjalainen, A Ples, H Pomposo, I Posti, J Puybasset, L Radoi, A Ragauskas, A Raj, R Rhodes, J Richter, S Rocka, S Roe, C Roise, O Rosenfeld, J Rosenlund, C Rosenthal, G Rossaint, R Rossi, S Sahuquillo, J Sandrød, O Sakowitz, O Sanchez-Porras, R Schirmer-Mikalsen, K Schou, R Smielewski, P Sorinola, A Stamatakis, E Sundström, N Takala, R Tamás, V Tamosuitis, T Tenovuo, O Thomas, M Tibboel, D Tolias, C Trapani, T Tudora, C Vajkoczy, P Vallance, S Valeinis, E Vámos, Z Van der Steen, G van Wijk, R Vargiolu, A Vega, E Vik, A Vilcinis, R Vulekovic, P Williams, G Winzeck, S Wolf, S Younsi, A Zeiler, F Ziverte, A Clusmann, H Voormolen, D van  Dijck, J van Essen, T Volovici, Victor Pisică, Dana Gravesteijn, Benjamin Y. Dirven, Clemens M. F. Steyerberg, Ewout W. Ercole, Ari Stocchetti, Nino Nelson, David Menon, David K. Citerio, Giuseppe van der Jagt, Mathieu Maas, Andrew I. R. Haitsma, Iain K. Lingsma, Hester F. Åkerlund, Cecilia Amrein, Krisztina Andelic, Nada Andreassen, Lasse Audibert, Gérard Azouvi, Philippe Azzolini, Maria Luisa Bartels, Ronald Beer, Ronny Bellander, Bo-Michael Benali, Habib Berardino, Maurizio Beretta, Luigi Beqiri, Erta Blaabjerg, Morten Lund, Stine Borgen Brorsson, Camilla Buki, Andras Cabeleira, Manuel Caccioppola, Alessio Calappi, Emiliana Calvi, Maria Rosa Cameron, Peter Lozano, Guillermo Carbayo Castaño-León, Ana M. Cavallo, Simona Chevallard, Giorgio Chieregato, Arturo Coburn, Mark Coles, Jonathan Cooper, Jamie D. Correia, Marta Czeiter, Endre Czosnyka, Marek Dahyot-Fizelier, Claire Dark, Paul De Keyser, Véronique Degos, Vincent Corte, Francesco Della Boogert, Hugo den Depreitere, Bart Dilvesi, Dula Dixit, Abhishek Dreier, Jens Dulière, Guy-Loup Ezer, Erzsébet Fabricius, Martin Foks, Kelly Frisvold, Shirin Furmanov, Alex Galanaud, Damien Gantner, Dashiell Ghuysen, Alexandre Giga, Lelde Golubovic, Jagos Gomez, Pedro A. Grossi, Francesca Gupta, Deepak Haitsma, Iain Helseth, Eirik Hutchinson, Peter J. Jankowski, Stefan Johnson, Faye Karan, Mladen Kolias, Angelos G. Kondziella, Daniel Koraropoulos, Evgenios Koskinen, Lars-Owe Kovács, Noémi Kowark, Ana Lagares, Alfonso Laureys, Steven Ledoux, Didier Lejeune, Aurelie Lightfoot, Roger Manara, Alex Martino, Costanza Maréchal, Hugues Mattern, Julia McMahon, Catherine Menovsky, Tomas Misset, Benoit Muraleedharan, Visakh Murray, Lynnette Negru, Ancuta Newcombe, Virginia Nyirádi, József Ortolano, Fabrizio Payen, Jean-François Perlbarg, Vincent Persona, Paolo Piippo-Karjalainen, Anna Ples, Horia Pomposo, Inigo Posti, Jussi P. Puybasset, Louis Radoi, Andreea Ragauskas, Arminas Raj, Rahul Rhodes, Jonathan Richter, Sophie Rocka, Saulius Roe, Cecilie Roise, Olav Rosenfeld, Jeffrey V. Rosenlund, Christina Rosenthal, Guy Rossaint, Rolf Rossi, Sandra Sahuquillo, Juan Sandrød, Oddrun Sakowitz, Oliver Sanchez-Porras, Renan Schirmer-Mikalsen, Kari Schou, Rico Frederik Smielewski, Peter Sorinola, Abayomi Stamatakis, Emmanuel Sundström, Nina Takala, Riikka Tamás, Viktória Tamosuitis, Tomas Tenovuo, Olli Thomas, Matt Tibboel, Dick Tolias, Christos Trapani, Tony Tudora, Cristina Maria Vajkoczy, Peter Vallance, Shirley Valeinis, Egils Vámos, Zoltán Van der Steen, Gregory van Wijk, Roel P. J. Vargiolu, Alessia Vega, Emmanuel Vik, Anne Vilcinis, Rimantas Vulekovic, Petar Williams, Guy Winzeck, Stefan Wolf, Stefan Younsi, Alexander Zeiler, Frederick A. Ziverte, Agate Clusmann, Hans Voormolen, Daphne Dijck, Jeroen T. J. M. van Essen, Thomas A. Volovici, V Pisică, D Gravesteijn, B Dirven, C Steyerberg, E Ercole, A Stocchetti, N Nelson, D Menon, D Citerio, G van der Jagt, M Maas, A Haitsma, I Lingsma, H Åkerlund, C Amrein, K Andelic, N Andreassen, L Audibert, G Azouvi, P Azzolini, M Bartels, R Beer, R Bellander, B Benali, H Berardino, M Beretta, L Beqiri, E Blaabjerg, M Lund, S Brorsson, C Buki, A Cabeleira, M Caccioppola, A Calappi, E Calvi, M Cameron, P Lozano, G Castaño-León, A Cavallo, S Chevallard, G Chieregato, A Coburn, M Coles, J Cooper, J Correia, M Czeiter, E Czosnyka, M Dahyot-Fizelier, C Dark, P De Keyser, V Degos, V Corte, F Boogert, H Depreitere, B Dilvesi, D Dixit, A Dreier, J Dulière, G Ezer, E Fabricius, M Foks, K Frisvold, S Furmanov, A Galanaud, D Gantner, D Ghuysen, A Giga, L Golubovic, J Gomez, P Grossi, F Gupta, D Helseth, E Hutchinson, P Jankowski, S Johnson, F Karan, M Kolias, A Kondziella, D Koraropoulos, E Koskinen, L Kovács, N Kowark, A Lagares, A Laureys, S Ledoux, D Lejeune, A Lightfoot, R Manara, A Martino, C Maréchal, H Mattern, J Mcmahon, C Menovsky, T Misset, B Muraleedharan, V Murray, L Negru, A Newcombe, V Nyirádi, J Ortolano, F Payen, J Perlbarg, V Persona, P Piippo-Karjalainen, A Ples, H Pomposo, I Posti, J Puybasset, L Radoi, A Ragauskas, A Raj, R Rhodes, J Richter, S Rocka, S Roe, C Roise, O Rosenfeld, J Rosenlund, C Rosenthal, G Rossaint, R Rossi, S Sahuquillo, J Sandrød, O Sakowitz, O Sanchez-Porras, R Schirmer-Mikalsen, K Schou, R Smielewski, P Sorinola, A Stamatakis, E Sundström, N Takala, R Tamás, V Tamosuitis, T Tenovuo, O Thomas, M Tibboel, D Tolias, C Trapani, T Tudora, C Vajkoczy, P Vallance, S Valeinis, E Vámos, Z Van der Steen, G van Wijk, R Vargiolu, A Vega, E Vik, A Vilcinis, R Vulekovic, P Williams, G Winzeck, S Wolf, S Younsi, A Zeiler, F Ziverte, A Clusmann, H Voormolen, D van  Dijck, J van Essen, T Volovici, Victor Pisică, Dana Gravesteijn, Benjamin Y. Dirven, Clemens M. F. Steyerberg, Ewout W. Ercole, Ari Stocchetti, Nino Nelson, David Menon, David K. Citerio, Giuseppe van der Jagt, Mathieu Maas, Andrew I. R. Haitsma, Iain K. Lingsma, Hester F. Åkerlund, Cecilia Amrein, Krisztina Andelic, Nada Andreassen, Lasse Audibert, Gérard Azouvi, Philippe Azzolini, Maria Luisa Bartels, Ronald Beer, Ronny Bellander, Bo-Michael Benali, Habib Berardino, Maurizio Beretta, Luigi Beqiri, Erta Blaabjerg, Morten Lund, Stine Borgen Brorsson, Camilla Buki, Andras Cabeleira, Manuel Caccioppola, Alessio Calappi, Emiliana Calvi, Maria Rosa Cameron, Peter Lozano, Guillermo Carbayo Castaño-León, Ana M. Cavallo, Simona Chevallard, Giorgio Chieregato, Arturo Coburn, Mark Coles, Jonathan Cooper, Jamie D. Correia, Marta Czeiter, Endre Czosnyka, Marek Dahyot-Fizelier, Claire Dark, Paul De Keyser, Véronique Degos, Vincent Corte, Francesco Della Boogert, Hugo den Depreitere, Bart Dilvesi, Dula Dixit, Abhishek Dreier, Jens Dulière, Guy-Loup Ezer, Erzsébet Fabricius, Martin Foks, Kelly Frisvold, Shirin Furmanov, Alex Galanaud, Damien Gantner, Dashiell Ghuysen, Alexandre Giga, Lelde Golubovic, Jagos Gomez, Pedro A. Grossi, Francesca Gupta, Deepak Haitsma, Iain Helseth, Eirik Hutchinson, Peter J. Jankowski, Stefan Johnson, Faye Karan, Mladen Kolias, Angelos G. Kondziella, Daniel Koraropoulos, Evgenios Koskinen, Lars-Owe Kovács, Noémi Kowark, Ana Lagares, Alfonso Laureys, Steven Ledoux, Didier Lejeune, Aurelie Lightfoot, Roger Manara, Alex Martino, Costanza Maréchal, Hugues Mattern, Julia McMahon, Catherine Menovsky, Tomas Misset, Benoit Muraleedharan, Visakh Murray, Lynnette Negru, Ancuta Newcombe, Virginia Nyirádi, József Ortolano, Fabrizio Payen, Jean-François Perlbarg, Vincent Persona, Paolo Piippo-Karjalainen, Anna Ples, Horia Pomposo, Inigo Posti, Jussi P. Puybasset, Louis Radoi, Andreea Ragauskas, Arminas Raj, Rahul Rhodes, Jonathan Richter, Sophie Rocka, Saulius Roe, Cecilie Roise, Olav Rosenfeld, Jeffrey V. Rosenlund, Christina Rosenthal, Guy Rossaint, Rolf Rossi, Sandra Sahuquillo, Juan Sandrød, Oddrun Sakowitz, Oliver Sanchez-Porras, Renan Schirmer-Mikalsen, Kari Schou, Rico Frederik Smielewski, Peter Sorinola, Abayomi Stamatakis, Emmanuel Sundström, Nina Takala, Riikka Tamás, Viktória Tamosuitis, Tomas Tenovuo, Olli Thomas, Matt Tibboel, Dick Tolias, Christos Trapani, Tony Tudora, Cristina Maria Vajkoczy, Peter Vallance, Shirley Valeinis, Egils Vámos, Zoltán Van der Steen, Gregory van Wijk, Roel P. J. Vargiolu, Alessia Vega, Emmanuel Vik, Anne Vilcinis, Rimantas Vulekovic, Petar Williams, Guy Winzeck, Stefan Wolf, Stefan Younsi, Alexander Zeiler, Frederick A. Ziverte, Agate Clusmann, Hans Voormolen, Daphne Dijck, Jeroen T. J. M. van Essen, Thomas A.
Publication Year :
2022
Abstract
Objective: To compare outcomes between patients with primary external ventricular device (EVD)–driven treatment of intracranial hypertension and those with primary intraparenchymal monitor (IP)–driven treatment. Methods: The CENTER-TBI study is a prospective, multicenter, longitudinal observational cohort study that enrolled patients of all TBI severities from 62 participating centers (mainly level I trauma centers) across Europe between 2015 and 2017. Functional outcome was assessed at 6 months and a year. We used multivariable adjusted instrumental variable (IV) analysis with “center” as instrument and logistic regression with covariate adjustment to determine the effect estimate of EVD on 6-month functional outcome. Results: A total of 878 patients of all TBI severities with an indication for intracranial pressure (ICP) monitoring were included in the present study, of whom 739 (84%) patients had an IP monitor and 139 (16%) an EVD. Patients included were predominantly male (74% in the IP monitor and 76% in the EVD group), with a median age of 46 years in the IP group and 48 in the EVD group. Six-month GOS-E was similar between IP and EVD patients (adjusted odds ratio (aOR) and 95% confidence interval [CI] OR 0.74 and 95% CI [0.36–1.52], adjusted IV analysis). The length of intensive care unit stay was greater in the EVD group than in the IP group (adjusted rate ratio [95% CI] 1.70 [1.34–2.12], IV analysis). One hundred eighty-seven of the 739 patients in the IP group (25%) required an EVD due to refractory ICPs. Conclusion: We found no major differences in outcomes of patients with TBI when comparing EVD-guided and IP monitor–guided ICP management. In our cohort, a quarter of patients that initially received an IP monitor required an EVD later for ICP control. The prevalence of complications was higher in the EVD group. Protocol: The core study is registered with ClinicalTrials.gov, number NCT02210221, and the Resource Identification Portal (RRID: SCR_015582).
Details
Database :
OAIster
Notes :
STAMPA, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1334334921
Document Type :
Electronic Resource