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Oncotype DX Predictive Nomogram for Recurrence Score Output: The Novel System ADAPTED01 Based on Quantitative Immunochemistry Analysis

Authors :
Marazzi, Fabio
Barone, R.
Masiello, V.
Magri, V.
Mule, A.
Santoro, Angela
Cacciatori, F.
Boldrini, Luca
Franceschini, Gianluca
Moschella, F.
Naso, G.
Tomao, S.
Gambacorta, Maria Antonietta
Mantini, Giovanna
Masetti, Riccardo
Smaniotto, Daniela
Valentini, Vincenzo
Marazzi F.
Santoro A. (ORCID:0000-0002-6964-5152)
Boldrini L.
Franceschini G. (ORCID:0000-0002-2950-3395)
Gambacorta M. A. (ORCID:0000-0001-5455-8737)
Mantini G. (ORCID:0000-0001-5303-4499)
Masetti R. (ORCID:0000-0002-7520-9111)
Smaniotto D. (ORCID:0000-0002-1246-8001)
Valentini V. (ORCID:0000-0003-4637-6487)
Marazzi, Fabio
Barone, R.
Masiello, V.
Magri, V.
Mule, A.
Santoro, Angela
Cacciatori, F.
Boldrini, Luca
Franceschini, Gianluca
Moschella, F.
Naso, G.
Tomao, S.
Gambacorta, Maria Antonietta
Mantini, Giovanna
Masetti, Riccardo
Smaniotto, Daniela
Valentini, Vincenzo
Marazzi F.
Santoro A. (ORCID:0000-0002-6964-5152)
Boldrini L.
Franceschini G. (ORCID:0000-0002-2950-3395)
Gambacorta M. A. (ORCID:0000-0001-5455-8737)
Mantini G. (ORCID:0000-0001-5303-4499)
Masetti R. (ORCID:0000-0002-7520-9111)
Smaniotto D. (ORCID:0000-0002-1246-8001)
Valentini V. (ORCID:0000-0003-4637-6487)
Publication Year :
2020

Abstract

A correlation between phenotypical tumor characteristics, quantitative classical immunohistochemistry (IHC), and recurrence score (RS) from Oncotype DX results was used to develop a decision supporting system for clinical use. We created a freely available nomogram based on quantitative IHC results that allows prediction of RS ≤ 25 or ≤ 20. Prospective studies will test this application in clinical practice.

Details

Database :
OAIster
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1330709484
Document Type :
Electronic Resource