Back to Search
Start Over
HLA-A*68:02-restricted Gag-specific cytotoxic T lymphocyte responses can drive selection pressure on HIV but are subdominant and ineffective
- Source :
- Kløverpris , H N , Buus , A S , Harndahl , M , Carlson , J M , Leslie , A J , Chen , F , Riddell , L , Mulenga , J , Walker , B D , Ndung'u , T , Buus , S & Goulder , P 2013 , ' HLA-A*68:02-restricted Gag-specific cytotoxic T lymphocyte responses can drive selection pressure on HIV but are subdominant and ineffective ' , AIDS (London, England) , vol. 27 , no. 11 , pp. 1717-23 .
- Publication Year :
- 2013
-
Abstract
- Human leukocyte allele (HLA) class I polymorphism has the greatest impact of human genetic variation on viral load set point. A substantial part of this effect is due to the action of HLA-B and HLA-C alleles. With few exceptions the role of HLA-A molecules in immune control of HIV is unclear.
Details
- Database :
- OAIster
- Journal :
- Kløverpris , H N , Buus , A S , Harndahl , M , Carlson , J M , Leslie , A J , Chen , F , Riddell , L , Mulenga , J , Walker , B D , Ndung'u , T , Buus , S & Goulder , P 2013 , ' HLA-A*68:02-restricted Gag-specific cytotoxic T lymphocyte responses can drive selection pressure on HIV but are subdominant and ineffective ' , AIDS (London, England) , vol. 27 , no. 11 , pp. 1717-23 .
- Notes :
- English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1322639855
- Document Type :
- Electronic Resource