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Night/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling
- Source :
- Bailey , M J , Coon , S L , Carter , J D , Humphries , A , Kim , J-S , Shi , Q , Gaildrat , P , Morin , F , Ganguly , S , Hogenesch , J B , Weller , J L , Rath , M F , Møller , M , Baler , R , Sugden , D , Rangel , Z G , Munson , P J & Klein , D C 2009 , ' Night/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling ' , Journal of Biological Chemistry , vol. 284 , no. 12 , pp. 7606-22 .
- Publication Year :
- 2009
-
Abstract
- The pineal gland plays an essential role in vertebrate chronobiology by converting time into a hormonal signal, melatonin, which is always elevated at night. Here we have analyzed the rodent pineal transcriptome using Affymetrix GeneChip(R) technology to obtain a more complete description of pineal cell biology. The effort revealed that 604 genes (1,268 probe sets) with Entrez Gene identifiers are differentially expressed greater than 2-fold between midnight and mid-day (false discovery rate
Details
- Database :
- OAIster
- Journal :
- Bailey , M J , Coon , S L , Carter , J D , Humphries , A , Kim , J-S , Shi , Q , Gaildrat , P , Morin , F , Ganguly , S , Hogenesch , J B , Weller , J L , Rath , M F , Møller , M , Baler , R , Sugden , D , Rangel , Z G , Munson , P J & Klein , D C 2009 , ' Night/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling ' , Journal of Biological Chemistry , vol. 284 , no. 12 , pp. 7606-22 .
- Notes :
- English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1322587892
- Document Type :
- Electronic Resource