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Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon
- Source :
- Jeppesen , P B , Hartmann , B , Thulesen , J , Graff , J , Lohmann , J , Hansen , B S , Tofteng , F , Poulsen , S S , Madsen , J L , Holst , J J & Mortensen , P B 2001 , ' Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon ' , Gastroenterology , vol. 120 , no. 4 , pp. 806-815 .
- Publication Year :
- 2001
-
Abstract
- Glucagon-like peptide 2 (GLP-2) is intestinotrophic, antisecretory, and transit-modulating in rodents, and it is mainly secreted from the intestinal mucosa of the terminal ileum and colon after food ingestion. We assessed the effect of GLP-2 on the gastrointestinal function in patients without a terminal ileum and colon who have functional short-bowel syndrome with severe malabsorption of wet weight (>1.5 kg/day) and energy (>2.3 MJ/day) and no postprandial secretion of GLP-2.
Details
- Database :
- OAIster
- Journal :
- Jeppesen , P B , Hartmann , B , Thulesen , J , Graff , J , Lohmann , J , Hansen , B S , Tofteng , F , Poulsen , S S , Madsen , J L , Holst , J J & Mortensen , P B 2001 , ' Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon ' , Gastroenterology , vol. 120 , no. 4 , pp. 806-815 .
- Notes :
- English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1322514973
- Document Type :
- Electronic Resource