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Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon

Authors :
Jeppesen, P B
Hartmann, B
Thulesen, J
Graff, J
Lohmann, J
Hansen, B S
Tofteng, F
Poulsen, Steen Seier
Madsen, J L
Holst, J J
Mortensen, P B
Jeppesen, P B
Hartmann, B
Thulesen, J
Graff, J
Lohmann, J
Hansen, B S
Tofteng, F
Poulsen, Steen Seier
Madsen, J L
Holst, J J
Mortensen, P B
Source :
Jeppesen , P B , Hartmann , B , Thulesen , J , Graff , J , Lohmann , J , Hansen , B S , Tofteng , F , Poulsen , S S , Madsen , J L , Holst , J J & Mortensen , P B 2001 , ' Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon ' , Gastroenterology , vol. 120 , no. 4 , pp. 806-815 .
Publication Year :
2001

Abstract

Glucagon-like peptide 2 (GLP-2) is intestinotrophic, antisecretory, and transit-modulating in rodents, and it is mainly secreted from the intestinal mucosa of the terminal ileum and colon after food ingestion. We assessed the effect of GLP-2 on the gastrointestinal function in patients without a terminal ileum and colon who have functional short-bowel syndrome with severe malabsorption of wet weight (>1.5 kg/day) and energy (>2.3 MJ/day) and no postprandial secretion of GLP-2.

Details

Database :
OAIster
Journal :
Jeppesen , P B , Hartmann , B , Thulesen , J , Graff , J , Lohmann , J , Hansen , B S , Tofteng , F , Poulsen , S S , Madsen , J L , Holst , J J & Mortensen , P B 2001 , ' Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon ' , Gastroenterology , vol. 120 , no. 4 , pp. 806-815 .
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1322514973
Document Type :
Electronic Resource