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Mass Oral Azithromycin for Childhood Mortality: Timing of Death After Distribution in the MORDOR Trial

Authors :
Porco, TC
Hart, J
Arzika, AM
Weaver, J
Kalua, K
Mrango, Z
Cotter, SY
Stoller, NE
O'Brien, KS
Fry, DM
Vanderschelden, B
Oldenburg, CE
West, SK
Bailey, RL
Keenan, JD
Lietman, TM
Porco, TC
Hart, J
Arzika, AM
Weaver, J
Kalua, K
Mrango, Z
Cotter, SY
Stoller, NE
O'Brien, KS
Fry, DM
Vanderschelden, B
Oldenburg, CE
West, SK
Bailey, RL
Keenan, JD
Lietman, TM
Publication Year :
2019

Abstract

In a large community-randomized trial, biannual azithromycin distributions significantly reduced postneonatal childhood mortality in sub-Saharan African sites. Here, we present a prespecified secondary analysis showing that much of the protective effect was in the first 3 months postdistribution. Distributing more frequently than biannually could be considered if logistically feasible. Clinical Trials Registration. NCT02047981.

Details

Database :
OAIster
Publication Type :
Electronic Resource
Accession number :
edsoai.on1315683913
Document Type :
Electronic Resource