Back to Search
Start Over
Control in the Hospital by Extensive Clinical rules for Unplanned hospitalizations in older Patients (CHECkUP): study design of a multicentre randomized study
- Source :
- Linkens , A E M J H , Milosevic , V , van Nie , N , Zwietering , A , de Leeuw , P W , van den Akker , M , Schols , J M G A , Evers , S M A A , Gonzalvo , C M , Winkens , B , van de Loo , B P A , de Wolf , L , Peeters , L , de Ree , M , Spaetgens , B , Hurkens , K P G M & van der Kuy , H M 2022 , ' Control in the Hospital by Extensive Clinical rules for Unplanned hospitalizations in older Patients (CHECkUP) : study design of a multicentre randomized study ' , BMC Geriatrics , vol. 22 , no. 1 , 36 .
- Publication Year :
- 2022
-
Abstract
- Background: Due to ageing of the population the incidence of multimorbidity and polypharmacy is rising. Polypharmacy is a risk factor for medication-related (re)admission and therefore places a significant burden on the healthcare system. The reported incidence of medication-related (re)admissions varies widely due to the lack of a clear definition. Some medications are known to increase the risk for medication-related admission and are therefore published in the triggerlist of the Dutch guideline for Polypharmacy in older patients. Different interventions to support medication optimization have been studied to reduce medication-related (re)admissions. However, the optimal template of medication optimization is still unknown, which contributes to the large heterogeneity of their effect on hospital readmissions. Therefore, we implemented a clinical decision support system (CDSS) to optimize medication lists and investigate whether continuous use of a CDSS reduces the number of hospital readmissions in older patients, who previously have had an unplanned probably medication-related hospitalization. Methods: The CHECkUP study is a multicentre randomized study in older (≥60 years) patients with an unplanned hospitalization, polypharmacy (≥5 medications) and using at least two medications from the triggerlist, from Zuyderland Medical Centre and Maastricht University Medical Centre+ in the Netherlands. Patients will be randomized. The intervention consists of continuous (weekly) use of a CDSS, which generates a Medication Optimization Profile, which will be sent to the patient’s general practitioner and pharmacist. The control group will receive standard care. The primary outcome is hospital readmission within 1 year after study inclusion. Secondary outcomes are one-year mortality, number of emergency department visits, nursing home admissions, time to hospital readmissions and we will evaluate the quality of life and socio-economic status. Discussion: This study is ex
Details
- Database :
- OAIster
- Journal :
- Linkens , A E M J H , Milosevic , V , van Nie , N , Zwietering , A , de Leeuw , P W , van den Akker , M , Schols , J M G A , Evers , S M A A , Gonzalvo , C M , Winkens , B , van de Loo , B P A , de Wolf , L , Peeters , L , de Ree , M , Spaetgens , B , Hurkens , K P G M & van der Kuy , H M 2022 , ' Control in the Hospital by Extensive Clinical rules for Unplanned hospitalizations in older Patients (CHECkUP) : study design of a multicentre randomized study ' , BMC Geriatrics , vol. 22 , no. 1 , 36 .
- Notes :
- application/pdf, English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1313639829
- Document Type :
- Electronic Resource