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Implementation of fetal clinical exome sequencing: Comparing prospective and retrospective cohorts.

Authors :
Marangoni, Martina
Smits, Guillaume
Ceysens, Gilles
Costa, Elena
Coulon, Robert
Daelemans, Caroline
De Coninck, Caroline
Derisbourg, Sara
Gajewska, Kalina
Garofalo, Giulia
Gounongbe, Caroline
Guizani, Meriem
Holoye, Anne
Houba, Catherine
Makhoul, Jean
Norgaard, Christian
Regnard, Cecile
Romée, Stephanie
Soto, Jamil
Stagel-Trabbia, Aurore
Van Rysselberge, Michel
Vercoutere, An
Zaytouni, Siham
Bouri, Sarah
D'Haene, Nicky
D'Onle, Dominique
Dugauquier, Christian
Racu, Marie-Lucie
Rocq, Laureen
Segers, Valérie
Verocq, Camille
Avni, Ephraïm Freddy
Cassart, Marie
Massez, Anne
Blaumeiser, Bettina
Brischoux-Boucher, Elise
Bulk, Saskia
De Ravel, Thomy
Debray, Francois-Guillaume
Dimitrov, Boyan
Janssens, Sandra
Keymolen, Kathelijn
Laterre, Marie
van Berkel, Kim
Van Maldergem, Lionel
Vandernoot, Isabelle
Vilain, Catheline
donner, catherine
Tecco, Laura
Thomas, Dominique
Désir, Julie
Abramowicz, Marc
Migeotte, Isabelle
Marangoni, Martina
Smits, Guillaume
Ceysens, Gilles
Costa, Elena
Coulon, Robert
Daelemans, Caroline
De Coninck, Caroline
Derisbourg, Sara
Gajewska, Kalina
Garofalo, Giulia
Gounongbe, Caroline
Guizani, Meriem
Holoye, Anne
Houba, Catherine
Makhoul, Jean
Norgaard, Christian
Regnard, Cecile
Romée, Stephanie
Soto, Jamil
Stagel-Trabbia, Aurore
Van Rysselberge, Michel
Vercoutere, An
Zaytouni, Siham
Bouri, Sarah
D'Haene, Nicky
D'Onle, Dominique
Dugauquier, Christian
Racu, Marie-Lucie
Rocq, Laureen
Segers, Valérie
Verocq, Camille
Avni, Ephraïm Freddy
Cassart, Marie
Massez, Anne
Blaumeiser, Bettina
Brischoux-Boucher, Elise
Bulk, Saskia
De Ravel, Thomy
Debray, Francois-Guillaume
Dimitrov, Boyan
Janssens, Sandra
Keymolen, Kathelijn
Laterre, Marie
van Berkel, Kim
Van Maldergem, Lionel
Vandernoot, Isabelle
Vilain, Catheline
donner, catherine
Tecco, Laura
Thomas, Dominique
Désir, Julie
Abramowicz, Marc
Migeotte, Isabelle
Source :
Genetics in medicine
Publication Year :
2021

Abstract

We compared the diagnostic yield of fetal clinical exome sequencing (fCES) in prospective and retrospective cohorts of pregnancies presenting with anomalies detected using ultrasound. We evaluated factors that led to a higher diagnostic efficiency, such as phenotypic category, clinical characterization, and variant analysis strategy.<br />SCOPUS: ar.j<br />info:eu-repo/semantics/published

Details

Database :
OAIster
Journal :
Genetics in medicine
Notes :
2 full-text file(s): application/pdf | application/pdf, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1313396924
Document Type :
Electronic Resource