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Population-based study of multisystem inflammatory syndrome associated with COVID-19 found that 36% of children had persistent symptoms

Authors :
Kahn, Robin
Berg, Stefan
Berntson, Lillemor
Berthold, Elisabet
Brodin, Petter
Bäckström, Fredrik
Compagno, Michele
Fasth, Anders
Lingman Framme, Jenny
Horne, AnnaCarin
Hätting, Josefin
Król, Petra
Kukka, Antti
Mossberg, Maria
Månsson, Bengt
Nordenhäll, Charlotta
Idring Nordström, Selma
Khammari Nyström, Fatine
Palmblad, Karin
Rasti, Reza
Rudolph, André
Rydenman, Karin
Sundberg, Erik
Säve-Söderbergh, Eva
Altman, Maria
Kahn, Robin
Berg, Stefan
Berntson, Lillemor
Berthold, Elisabet
Brodin, Petter
Bäckström, Fredrik
Compagno, Michele
Fasth, Anders
Lingman Framme, Jenny
Horne, AnnaCarin
Hätting, Josefin
Król, Petra
Kukka, Antti
Mossberg, Maria
Månsson, Bengt
Nordenhäll, Charlotta
Idring Nordström, Selma
Khammari Nyström, Fatine
Palmblad, Karin
Rasti, Reza
Rudolph, André
Rydenman, Karin
Sundberg, Erik
Säve-Söderbergh, Eva
Altman, Maria
Publication Year :
2022

Abstract

Aim: Our aim was to describe the outcomes of multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19. Methods: This national, population-based, longitudinal, multicentre study used Swedish data that were prospectively collected between 1 December 2020 and 31 May 2021. All patients met the World Health Organization criteria for MIS-C. The outcomes 2 and 8 weeks after diagnosis are presented, and follow-up protocols are suggested. Results: We identified 152 cases, and 133 (87%) participated. When followed up 2 weeks after MIS-C was diagnosed, 43% of the 119 patients had abnormal results, including complete blood cell counts, platelet counts, albumin levels, electrocardiograms and echocardiograms. After 8 weeks, 36% of 89 had an abnormal patient history, but clinical findings were uncommon. Echocardiogram results were abnormal in 5% of 67, and the most common complaint was fatigue. Older children and those who received intensive care were more likely to report symptoms and have abnormal cardiac results. Conclusion: More than a third (36%) of the patients had persistent symptoms 8 weeks after MIS-C, and 5% had abnormal echocardiograms. Older age and higher levels of initial care appeared to be risk factors. Structured follow-up visits are important after MIS-C.

Details

Database :
OAIster
Notes :
application/pdf, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1312840568
Document Type :
Electronic Resource
Full Text :
https://doi.org/10.1111.apa.16191