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A Family of Sugar-Based Molecules for Therapeutic Use and Process for the Production Thereof

Authors :
Nicotra, F
LA FERLA, B
Pitaro, M
Salvetti, M
Codacci Pisanelli, G
Ristori, G
NICOTRA, FRANCESCO
LA FERLA, BARBARA
Ristori, G.
Nicotra, F
LA FERLA, B
Pitaro, M
Salvetti, M
Codacci Pisanelli, G
Ristori, G
NICOTRA, FRANCESCO
LA FERLA, BARBARA
Ristori, G.
Publication Year :
2012

Abstract

The present invention concerns a family of sugar-based molecules for therapeutic use, comprising compounds with a structure having at least one sugar molecule with carrier function, bound to arsenic having active principle function, allowing the selective therapeutic treatment of tumoral pathologies and not, distinguished by a high cellular metabolism and, consequently, by a high glucose consumption. On the base of the preferential glucose absorption according to the Warburg effect, said compounds are adapted to penetrate inside tumoral cells and not, distinguished by a high cellular metabolism, by means of the glucose molecule integrated in their structure, so as to determine the selective therapeutic treatment of said cells and, consequently, of the pathologies deriving therefrom, by means of the arsenic molecule chemically bound to above mentioned glucose molecule.; Also a process for the production of synthetic sugar-based compounds is the object of the present invention, as well as a process for the production of extracted sugar-based compounds, produced from natural sources

Details

Database :
OAIster
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1311390259
Document Type :
Electronic Resource