Young women's psychological distress after a diagnosis of polycystic ovary syndrome or endometriosis.

Study question: Do young women with polycystic ovary syndrome (PCOS) or endometriosis report more psychological distress than their peers without a history of these conditions? summaryanswer: Youngwomen(aged 18-23 years) withPCOSor endometriosis had a greater risk ofmoderate to severe psychological distress than women without a history of these conditions. what is known already: Psychological distress appears common among women with PCOS and endometriosis. However, population- based studies that examine the psychological outcomes for adolescents and young women are generally absent from the literature. study design, size, duration: This is a secondary analysis of data collected from 17 015 young, Australian women participating in a national, longitudinal cohort study.Womenwere first surveyed in 2012-2013 when they were aged 18-23 years. In 2014,womencompleted the second survey when they were aged 19-24 years and 11324 (67%) women responded. participants/materials, setting, methods:We analysed data from11 238 women who participated in both Surveys 1 and 2 and who responded to questions about PCOS and endometriosis. Using logistic regression, we compared the odds of moderate to severe psychological distress at Surveys 1 and 2 for women reporting a recent diagnosis (within the last 12 months) of PCOS or endometriosis and women with a pre-existing diagnosis, with that for women without a history of these conditions. main results and the role of chance: At Survey 2, around 60% of women reporting a diagnosis of PCOSor endometriosis had moderate to severe levels of psychological distress. Compared to women without a history of these conditions, the odds of moderate to severe psychological distress at Survey 2 were significantly higher for women recently diagnosed with PCOS [Adjusted Odds Ratio (AOR) = 1.62, 95% CI = 1.21-2.18] or endometriosis (AOR= 1.77; 95% CI = 1.20-2.63) and for women with a pre-existing diagnosis of PCOS (AOR = 1.57, 95% CI = 1.30-1.89) or endometrios