Long-term results of Phase II study of high dose photon/proton radiotherapy in the management of spine chordomas, chondrosarcomas, and other sarcomas

Negative surgical margins are uncommon for spine sarcomas; hence, adjuvant radiotherapy (RT) may be recommended but tumor dose may be constrained by spinal cord, nerve and viscera tolernce. Prospective Phase II clinical trial incorporating high dose RT. Eligible patients had primary or locally recorrent thoracic, lumbar, and/or sacral spine-paraspinal chordomas or sarcomas. Treatment included pre-and/or post-operative photon/proton RT += radical resection.