Diet and biliary tract cancer

RIVM rapport:We studied the relation between diet and biliary tract cancer in a case-control study, comprising 111 incident cases and 480 controls from the general population. Food intake was assessed with a semi- quantitative food frequency questionnaire, which covered diet comprehensively. In half of the cases and 30% of the controls the information was obtained from the spouse or other relatives (indirect respondents). Mono- and disaccharides showed an elevated risk, independent from other sources of energy. Vegetables and beta-carotene showed a reduced risk. Associations were stronger among the indirect respondents. Findings on mono-disaccharides were discussed in connection with bloodlipids, bile composition and gallstone formation.