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detectRUNS: Detect runs of homozygosity and runs of heterozygosity in diploid genomes

Authors :
Biscarini, Filippo
Cozzi, Paolo
Gaspa, Giustino
Marras, Gabriele
Biscarini, Filippo
Cozzi, Paolo
Gaspa, Giustino
Marras, Gabriele

Abstract

detectRUNS is a R package for the detection of runs of homozygosity (ROH/ROHom) and of heterozygosity (ROHet, a.k.a. “heterozygosity-rich regions”) in diploid genomes. ROH/ROHom were first studied in humans (e.g. McQuillan et al. 2008) and rapidly found applications not only in human genetics abut also in animal genetics (e.g. Ferencakovic et al., 2011, in Bos taurus). More recently, the idea of looking also at “runs of heterozygosity” (ROHet or, more appropriately, “heterozygosity-rich regions”) has been proposed (Wiliams et al. 2016).

Details

Database :
OAIster
Notes :
application/pdf, Biscarini, Filippo ORCID: https://orcid.org/0000-0002-3901-2354 , Cozzi, Paolo, Gaspa, Giustino and Marras, Gabriele 2018. detectRUNS: Detect runs of homozygosity and runs of heterozygosity in diploid genomes. CRAN (The Comprehensive R Archive Network). file , English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1296658413
Document Type :
Electronic Resource