Role of Therapeutic Drug Monitoring and Challenges in the Management of Infantile Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML) is a rare pediatric cancer, more so in children below four years of age. Treating infants with CML can be challenging especially with ensuring compliance to therapy. We report two infants with adult type CML and the role of therapeutic drug monitoring (TDM) during tyrosine kinase inhibitor therapy (TKI) therapy in their treatment.