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Mucosal HIV-1 Pox Virus Prime-Boost Immunization Induces High-Avidity CD8 + T Cells with Regime-Dependent Cytokine/Granzyme B Profiles

Authors :
Turner, Stephen
McArthur, Craig
Sutherland, Duncan
Kim, Jee-Hye
Doherty, Peter
Ramshaw, Ian
Ranasinghe, Charani
Turner, Stephen
McArthur, Craig
Sutherland, Duncan
Kim, Jee-Hye
Doherty, Peter
Ramshaw, Ian
Ranasinghe, Charani
Source :
Journal of Immunology
Publication Year :
2007

Abstract

The quality of virus-specific CD8+ CTL immune responses generated by mucosal and systemic poxvinis prime-boost vaccines were evaluated in terms of T cell avidity and single-cell analysis of effector gene expression. Intranasal (I.N.) immunization regimes

Details

Database :
OAIster
Journal :
Journal of Immunology
Publication Type :
Electronic Resource
Accession number :
edsoai.on1291759251
Document Type :
Electronic Resource