Comment on: 'Pathological features of 11,337 patients with primary ductal carcinoma in situ (DCIS) and subsequent events: results from the UK Sloane Project'.

We read with great interest the report by Shaaban et al. on the UK Sloane Project.1 This unique prospective cohort of DCIS patients provides an unprecedented view on the real-world management and long-term follow-up of this pre-invasive disease. The Sloane Project provides an immense amount of valuable data.1 Although Shaaban and colleagues have extensively discussed their observations, we would like to focus on an interesting finding that was slightly neglected in the discussion, likely because it seems very banal at first glance. We use this particular observation to launch a new research hypothesis by emphasising the similarities between recurrence after breast-conserving surgery (BCS) for DCIS and intrahepatic recurrence after partial hepatectomy for hepatocellular carcinoma (HCC). [...]