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On the many advantages of using the VariantExperiment class to store, exchange and analyze SARS-CoV-2 genomic data and associated metadata

Authors :
UCL - SSS/IREC/CTMA - Centre de technologies moléculaires appliquées (plate-forme technologique)
UCL - SSS/DDUV/CBIO - Computational Biology and Bioinformatics
Ambroise, Jérôme
Gatto, Laurent
Hurel, Julie
Bearzatto, Bertrand
Gala, Jean-Luc
UCL - SSS/IREC/CTMA - Centre de technologies moléculaires appliquées (plate-forme technologique)
UCL - SSS/DDUV/CBIO - Computational Biology and Bioinformatics
Ambroise, Jérôme
Gatto, Laurent
Hurel, Julie
Bearzatto, Bertrand
Gala, Jean-Luc
Source :
biorXiv,
Publication Year :
2021

Abstract

On Friday, 19 March 2021, WHO organized a virtual global workshop highlighting the need for a globally coordinated plan to increase SARS-CoV-2 genetic sequencing capacities to detect SARS-CoV-2 mutations and variants, and to monitor virus genomic evolution worldwide. One week later, in another virtual meeting, it focused on sero epidemiology for SARS-CoV-2 variants of concern and variants of interest. Efficient monitoring of the virus relies on the storage, handling and sharing of the genomic data and the associated metadata. In this manuscript, we demonstrate how the Bioconductor VariantExperiment class addresses these needs, offering a robust and efficient solution to the requirements laid out by the WHO.

Details

Database :
OAIster
Journal :
biorXiv,
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1288277784
Document Type :
Electronic Resource