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Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome

Authors :
Wiencke, John
Wiencke, John
MacHiela, MJ
Zhou, W
Karlins, E
Sampson, JN
Freedman, ND
Yang, Q
Hicks, B
Dagnall, C
Hautman, C
Jacobs, KB
Wiencke, John
Wiencke, John
MacHiela, MJ
Zhou, W
Karlins, E
Sampson, JN
Freedman, ND
Yang, Q
Hicks, B
Dagnall, C
Hautman, C
Jacobs, KB
Publication Year :
2016

Abstract

To investigate large structural clonal mosaicism of chromosome X, we analysed the SNP microarray intensity data of 38,303 women from cancer genome-wide association studies (20,878 cases and 17,425 controls) and detected 124 mosaic X events >2 Mb in 97 (0.2

Details

Database :
OAIster
Publication Type :
Electronic Resource
Accession number :
edsoai.on1287518973
Document Type :
Electronic Resource