Back to Search
Start Over
Dietary glycaemic index, glycaemic load and head and neck cancer risk: a pooled analysis in an international consortium.
- Source :
- British journal of cancer; vol 122, iss 6, 745-748; 0007-0920
- Publication Year :
- 2020
-
Abstract
- High dietary glycaemic index (GI) and glycaemic load (GL) may increase cancer risk. However, limited information was available on GI and/or GL and head and neck cancer (HNC) risk. We conducted a pooled analysis on 8 case-control studies (4081 HNC cases; 7407 controls) from the International Head and Neck Cancer Epidemiology (INHANCE) consortium. We estimated the odds ratios (ORs) and 95% confidence intervals (CIs) of HNC, and its subsites, from fixed- or mixed-effects logistic models including centre-specific quartiles of GI or GL. GI, but not GL, had a weak positive association with HNC (ORQ4 vs. Q1 = 1.16; 95% CI = 1.02-1.31). In subsites, we found a positive association between GI and laryngeal cancer (ORQ4 vs. Q1 = 1.60; 95% CI = 1.30-1.96) and an inverse association between GL and oropharyngeal cancer (ORQ4 vs. Q1 = 0.78; 95% CI = 0.63-0.97). This pooled analysis indicates a modest positive association between GI and HNC, mainly driven by laryngeal cancer.
Details
- Database :
- OAIster
- Journal :
- British journal of cancer; vol 122, iss 6, 745-748; 0007-0920
- Notes :
- application/pdf, British journal of cancer vol 122, iss 6, 745-748 0007-0920
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1287300537
- Document Type :
- Electronic Resource