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Safety of Chloroquine or Hydroxychloroquine Plus Azithromycin for the Treatment of COVID-19 Patients in Burkina Faso: An Observational Prospective Cohort Study

Authors :
Rouamba,Toussaint
Barry,Houreratou
Ouédraogo,Espérance
Tahita,Marc Christian
Yaméogo,Nobila Valentin
Poda,Armel
Diendéré,Eric Arnaud
Ouedraogo,Abdoul-Salam
Valea,Innocent
Koné,Amariane M
Thiombiano,Cherileila
Traoré,Isidore
Tarnagda,Zekiba
Sawadogo,Serge Aimé
Gansané,Zakaria
Kambiré,Yibar
Sanou,Idrissa
Barro-Traoré,Fatou
Drabo,Maxime K
Tinto,Halidou
Rouamba,Toussaint
Barry,Houreratou
Ouédraogo,Espérance
Tahita,Marc Christian
Yaméogo,Nobila Valentin
Poda,Armel
Diendéré,Eric Arnaud
Ouedraogo,Abdoul-Salam
Valea,Innocent
Koné,Amariane M
Thiombiano,Cherileila
Traoré,Isidore
Tarnagda,Zekiba
Sawadogo,Serge Aimé
Gansané,Zakaria
Kambiré,Yibar
Sanou,Idrissa
Barro-Traoré,Fatou
Drabo,Maxime K
Tinto,Halidou
Publication Year :
2021

Abstract

Toussaint Rouamba,1,* Houreratou Barry,2,* Esperance Ouédraogo,1 Marc Christian Tahita,1 Nobila Valentin Yaméogo,3 Armel Poda,4 Arnaud Eric Diendéré,5 Abdoul-Salam Ouedraogo,4 Innocent Valea,1 Amariane M Koné,2 Cherileila Thiombiano,2 Isidore Traoré,2 Zekiba Tarnagda,1 Serge A Sawadogo,6 Zakaria Gansané,7 Yibar Kambiré,8 Idrissa Sanou,8 Fatou Barro-Traoré,8 Maxime K Drabo,1 Halidou Tinto1 On behalf of the CHLORAZ Study Group1Institut de Recherche en Sciences de la Santé (CNRST-IRSS), Nanoro, Burkina Faso; 2Institut National de Santé Publique, Centre Muraz, Bobo-Dioulasso, Burkina Faso; 3Centre Hospitalier Universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso; 4Centre Hospitalier Universitaire Sourou Sanon, Bobo-Dioulasso, Burkina Faso; 5Centre Hospitalier Universitaire de Bogodogo, Ouagadougou, Burkina Faso; 6Centre PrïmO Nelson Mandela (Promotion de la Recherche et de l’Innovation en Immunologie Médicale de Ouagadougou), Ouagadougou, Burkina Faso; 7Clinical Monitoring in Africa-Clinical Research Organization, Ouagadougou, Burkina Faso; 8Centre Hospitalier Universitaire de Tengandogo, Ouagadougou, Burkina Faso*These authors contributed equally to this workCorrespondence: Toussaint RouambaInstitut de Recherche en Sciences de la Santé (CNRST-IRSS), 528, Avenue Kumda-Yoore, BP 218 Ouagadougou CMS 11, Ouagadougou, Nanoro, Burkina FasoTel +226 666 532 04Email rouambatoussaint@gmail.comIntroduction: Though chloroquine derivatives are used in the treatment of coronavirus disease 2019 (COVID-19) in many countries worldwide, doubts remain about the safety and efficacy of these drugs, especially in African communities where published data are scarce.Methods: We conducted an observational prospective cohort study from April 24 to September 03, 2020, in Burkina Faso to assess (as primary outcome) the clinical, biological, and cardiac (electrocardiographic) safety of chloroquine or hydroxychloroquine plus azithromycin administered to

Details

Database :
OAIster
Notes :
text/html, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1286361027
Document Type :
Electronic Resource