Back to Search
Start Over
Risk stratification with cervical length and fetal fibronectin in women with threatened preterm labor before 34 weeks and not delivering within 7 days
- Source :
- Acta Obstetricia et Gynecologica Scandinavica; 715; 721; 0001-6349; 7; 94; ~Acta Obstetricia et Gynecologica Scandinavica~715~721~~~0001-6349~7~94~~
- Publication Year :
- 2015
-
Abstract
- Item does not contain fulltext<br />OBJECTIVE: To stratify the risk of spontaneous preterm delivery using cervical length (CL) and fetal fibronectin (fFN) in women with threatened preterm labor who remained pregnant after 7 days. DESIGN: Prospective observational study. SETTING: Nationwide cohort of women with threatened preterm labor from the Netherlands. POPULATION: Women with threatened preterm labor between 24 and 34 weeks with a valid CL and fFN measurement and remaining pregnant 7 days after admission. METHODS: Kaplan-Meier and Cox proportional hazards models were used to estimate cumulative percentages and hazard ratios (HR) for spontaneous delivery. MAIN OUTCOME MEASURES: Spontaneous delivery between 7 and 14 days after initial presentation and spontaneous preterm delivery before 34 weeks. RESULTS: The risk of delivery between 7 and 14 days was significantly increased for women with a CL < 15 mm or a CL >/=15 to <30 mm and a positive fFN, compared with women with a CL >/=30 mm: HR 22.3 [95% confidence interval (CI) 2.6-191] and 14 (95% CI 1.8-118), respectively. For spontaneous preterm delivery before 34 weeks the risk was increased for women with a CL < 15 mm [HR 6.3 (95% CI 2.6-15)] or with a CL >/=15 to <30 mm with either positive fFN [HR 3.6 (95% CI 1.5-8.7)] or negative fFN [HR 3.0 (95% CI 1.2-7.1)] compared with women with a CL >/= 30 mm. CONCLUSIONS: In women remaining pregnant 7 days after threatened preterm labor, CL and fFN results can be used in risk stratification for spontaneous delivery.
Details
- Database :
- OAIster
- Journal :
- Acta Obstetricia et Gynecologica Scandinavica; 715; 721; 0001-6349; 7; 94; ~Acta Obstetricia et Gynecologica Scandinavica~715~721~~~0001-6349~7~94~~
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1284027789
- Document Type :
- Electronic Resource