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Cell-laden alginate hydrogels for the treatment of diabetes

Authors :
Izeia, Lukin
da Silva, Tatiane Eufrásio
Dolatshahi-Pirouz, Alireza
Ostrovidov, Serge
Paolone, Giovanna
Peppas, Nicholas A.
De Vos, Paul
Emerich, Dwaine
Orive, Gorka
Izeia, Lukin
da Silva, Tatiane Eufrásio
Dolatshahi-Pirouz, Alireza
Ostrovidov, Serge
Paolone, Giovanna
Peppas, Nicholas A.
De Vos, Paul
Emerich, Dwaine
Orive, Gorka
Source :
Izeia , L , da Silva , T E , Dolatshahi-Pirouz , A , Ostrovidov , S , Paolone , G , Peppas , N A , De Vos , P , Emerich , D & Orive , G 2020 , ' Cell-laden alginate hydrogels for the treatment of diabetes ' , Expert Opinion on Drug Delivery , vol. 17 , no. 8 , pp. 1113-1118 .
Publication Year :
2020

Abstract

Introduction: Diabetes mellitus is an ever-increasing medical condition that currently suffers 1 of 11 adults who may have lifelong commitment with insulin injections. Cell-laden hydrogels releasing insulin may provide the ultimate means of correcting diabetes. Here, we provide insights of this cell-based approach including latest preclinical and clinical progress both from academia and industry. Area covered: The present article focuses on reviewing latest advances in cell-laden hydrogels both from the technological and biological perspective. The most relevant clinical results including clinical trials are also discussed. Expert opinion: Current progress in technological issues (stem cells, devices, biomaterials) have contributed cell encapsulation science to have a very relevant progress in the field of diabetes treatment.

Details

Database :
OAIster
Journal :
Izeia , L , da Silva , T E , Dolatshahi-Pirouz , A , Ostrovidov , S , Paolone , G , Peppas , N A , De Vos , P , Emerich , D & Orive , G 2020 , ' Cell-laden alginate hydrogels for the treatment of diabetes ' , Expert Opinion on Drug Delivery , vol. 17 , no. 8 , pp. 1113-1118 .
Notes :
application/pdf, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1280589860
Document Type :
Electronic Resource