High Uric Acid Level Predicts Early Neurological Deterioration in Intracerebral Hemorrhage

Xiuqun Gong,1,* Zeyu Lu,2,* Xiwu Feng,3,* Kang Yuan,4 Mei Zhang,1 Xiaosi Cheng,1 Min Xue,1 Liang Yu,1 Jun Lu,5,6 Chuanqing Yu1 1Department of Neurology, First Affiliated Hospital of Anhui University of Science and Technology, First People’s Hospital of Huainan, Huainan, People’s Republic of China; 2College of Medicine, Anhui University of Science and Technology, Huainan, People’s Republic of China; 3Department of Cardiothoracic Surgery, First Affiliated Hospital of Anhui University of Science and Technology, First People’s Hospital of Huainan, Huainan, People’s Republic of China; 4Department of Neurology, Jinling Hospital, Nanjing Medical University, Nanjing, People’s Republic of China; 5Department of Medical Laboratory, College of Medicine, Anhui University of Science and Technology, Huainan, People’s Republic of China; 6Department of Clinical Laboratory, First Affiliated Hospital of Anhui University of Science and Technology, First People’s Hospital of Huainan, Huainan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jun LuDepartment of Medical Laboratory, College of Medicine, Anhui University of Science and Technology, 168 Taifeng Road, Huainan, 232001, Anhui Province, People’s Republic of ChinaTel + 86- 13855453149Email cfdxlujun@126.comChuanqing YuDepartment of Neurology, First Affiliated Hospital of Anhui University of Science and Technology, First People’s Hospital of Huainan, 203 Huaibin Road, Huainan, 232007, Anhui Province, People’s Republic of ChinaTel +86- 18949669880Email yuchuanqin1967@163.comObjective: Increased level of serum uric acid (UA) is often considered a risk factor for ischemic stroke. However, there are limited data on the association between UA and intracerebral hemorrhage (ICH). This study aimed to examine the connection between UA and early neurological deterioration (END) in patients with ICH.Methods: This is a prospective observational stud