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What is a clinically relevant change on the HIT-6 questionnaire? An estimation in a primary-care population of migraine patients
- Source :
- Cephalalgia; 29; 36; 0333-1024; 1; 34; ~Cephalalgia~29~36~~~0333-1024~1~34~~
- Publication Year :
- 2014
-
Abstract
- Item does not contain fulltext<br />OBJECTIVE: To interpret questionnaire scores, clinicians and researchers need to know what change in score reflects a meaningful change in the condition of an individual patient, and what difference reflects a meaningful difference between groups. These values differ between different populations. We determined the within-person minimally important change (MIC) and the between-group minimally important difference (MID) of the Headache Impact Test-6 (HIT-6) questionnaire in a primary-care population of migraine patients. METHODS: We included 490 patients who participated in a clinical trial on the treatment of migraine in primary care. We compared their change scores on the HIT-6 questionnaire between baseline and at three-months follow-up with the answers to two anchor questions according to the 'mean change approach' and the 'ROC curve approach'. RESULTS: The within-person MIC was estimated to be between -2.5 points (mean change approach) and -6 points (ROC curve approach). The choice for the within-person MIC value depends on the consequences of false positives and false negatives in a particular setting. The between-group MID was estimated at -1.5 points. CONCLUSIONS: We determined the within-person MIC and between-group MID for the HIT-6 in a primary-care population of migraine patients. We recommend the use of these values for clinical care and for research.
Details
- Database :
- OAIster
- Journal :
- Cephalalgia; 29; 36; 0333-1024; 1; 34; ~Cephalalgia~29~36~~~0333-1024~1~34~~
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1247336131
- Document Type :
- Electronic Resource