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Neurological features in SARS-CoV-2-infected patients with smell and taste disorder
- Publication Year :
- 2020
-
Abstract
- By the end of February 2020, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) raided Northern Italy causing an exponential increase of cases. Newonset smell and taste disorders (STD) are common findings in SARS-CoV-2 patients [2], whereas severe neurological symptoms are less commonly observed. The question has been raised whether mild neurological symptoms indicate a neuroinvasive potential of SARS-CoV-2. Ability to invade the central nervous system (CNS) through the olfactory neuroepithelium has been demonstrated for previous strains of coronavirus [3]. Furthermore, nasal epithelial cells display a high expression of the SARS-CoV-2 receptor, angiotensinconverting enzyme 2. CNS involvement is supported by the observation of MRI abnormalities in the olfactory bulb of some patients with SARS-CoV-2 infection and STD. We studied a cohort of SARS-CoV-2-infected patients with new-onset STD.
Details
- Database :
- OAIster
- Notes :
- English
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1242038720
- Document Type :
- Electronic Resource