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Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

Authors :
Bertilsson, G
Heidrich, J
Svensson, K
Asman, M
Jendeberg, L
Sydow-Backman, M
Ohlsson, R
Postlind, H
Blomquist, P
Berkenstam, A
Bertilsson, G
Heidrich, J
Svensson, K
Asman, M
Jendeberg, L
Sydow-Backman, M
Ohlsson, R
Postlind, H
Blomquist, P
Berkenstam, A
Publication Year :
1998

Abstract

Nuclear receptors regulate metabolic pathways in response to changes in the environment by appropriate alterations in gene expression of key metabolic enzymes, Here, a computational search approach based on iteratively built hidden Markov models of nuclea<br />Addresses: Berkenstam A, Pharmacia & Upjohn Inc, Dept Mol Biol & Genomics, S-11287 Stockholm, Sweden. Pharmacia & Upjohn Inc, Dept Mol Biol & Genomics, S-11287 Stockholm, Sweden. Pharmacia & Upjohn Inc, Dept Biochem & Cell Biol, S-11287 Stockholm, Sweden.

Details

Database :
OAIster
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1234631410
Document Type :
Electronic Resource