Ocular Manifestations of Sarcoidosis in a South Florida Population

Diana Laura,1,2 Yonghoon Lee,1,2 Monika Farhangi,1,2 Oriana Salamo,1 Mehdi Mirsaeidi,1,3 Raquel Goldhardt,1,2 Anat Galor1,2 1Miami Veterans Administration Medical Center, Miami, FL 33125, USA; 2Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami, Miami, FL 33136, USA; 3Department of Pulmonology, University of Miami, Miami, FL 33125, USACorrespondence: Anat GalorMiami Veterans Administration Medical Center, 1201 NW 16th St, Miami, FL 33125, USAEmail agalor@med.miami.eduObjective: To describe the ocular manifestations of sarcoidosis in a South Florida population and identify risk factors for the presence of ocular disease.Design: Retrospective consecutive case series.Methods: Medical charts of individuals with sarcoidosis seen in the University of Miami pulmonary department were reviewed for ocular disease. Odds ratios were used to identify risk factors for ocular sarcoidosis.Results: Fourteen of 108 individuals with sarcoidosis had ocular involvement. The mean age of the 14 individuals was 56± 15 years. Seventy-one percent were female, 50% were black, and 21% were Hispanic. Twelve had uveitis of which panuveitis was the most common subtype. Five had ≤ 20/70 vision in at least one eye due to uveitis. Neurosarcoidosis was a risk factor for ocular sarcoidosis (OR 6.14, p=0.03, 95% CI 1.21– 31.09).Conclusion: Ocular manifestations occurred in a minority of individuals in a pulmonary sarcoidosis clinic in South Florida. Uveitis was the most common ocular manifestation. Neurosarcoidosis was a risk factor for ocular involvement.Keywords: neurosarcoidosis, sarcoidosis, ocular sarcoidosis, uveitis