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Pigs are not susceptible to SARS‐CoV‐2 infection but are a model for viral immunogenicity studies

Authors :
Barcelona Supercomputing Center
Vergara-Alert, Júlia
Rodon, Jordi
Carrillo, Jorge
Te, Nigeer
Izquierdo‐Useros, Nuria
Rodríguez de la Concepción, María Luisa
Ávila‐Nieto, Carlos
Guallar, Victor
Valencia, Alfonso
Cantero, Guillermo
Blanco, Julià
Clotet, Bonaventura
Bensaid, Albert
Segalés, Joaquim
Barcelona Supercomputing Center
Vergara-Alert, Júlia
Rodon, Jordi
Carrillo, Jorge
Te, Nigeer
Izquierdo‐Useros, Nuria
Rodríguez de la Concepción, María Luisa
Ávila‐Nieto, Carlos
Guallar, Victor
Valencia, Alfonso
Cantero, Guillermo
Blanco, Julià
Clotet, Bonaventura
Bensaid, Albert
Segalés, Joaquim
Publication Year :
2020

Abstract

Conventional piglets were inoculated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) through different routes, including intranasal, intratracheal, intramuscular and intravenous ones. Although piglets were not susceptible to SARS‐CoV‐2 and lacked lesions or viral RNA in tissues/swabs, seroconversion was observed in pigs inoculated parenterally (intramuscularly or intravenously).<br />The CBIG Consortium (constituted by IRTA‐CReSA, BSC, & IrsiCaixa) is supported by Grifols pharmaceutical. The authors also acknowledge the crowdfunding initiative of https://www.yomecorono.com.<br />Peer Reviewed<br />Postprint (published version)

Details

Database :
OAIster
Notes :
5 p., application/pdf, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1224046867
Document Type :
Electronic Resource