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Fluorinated carbohydrates as chemical probes formolecular recognition studies. Current statusand perspectives

Authors :
Química orgánica II
Kimika organikoa II
Linclau, Bruno
Ardá, Ana
Reichardt, Niels Christian
Sollogoub, Matthieu
Unione, Luca
Vincent, Stéphane P.
Jiménez Barbero, Jesús
Química orgánica II
Kimika organikoa II
Linclau, Bruno
Ardá, Ana
Reichardt, Niels Christian
Sollogoub, Matthieu
Unione, Luca
Vincent, Stéphane P.
Jiménez Barbero, Jesús
Publication Year :
2020

Abstract

This review provides an extensive summary of the effects of carbohydrate fluorination with regard to changes in physical, chemical and biological properties with respect to regular saccharides. The specific structural, conformational, stability, reactivity and interaction features of fluorinated sugars are described, as well as their applications as probes and in chemical biology.

Details

Database :
OAIster
Notes :
B. L. thanks the EPSRC (EP/P019943/1) for funding. L. U. acknowledges funding from the postdoctoral fellowship from the Human Frontier Science Program Organization (HFSP) Grant No. LT000747/2018-C. N. C. R. acknowledges funding from Agencia Estatal de Investigacion (Spain) Grant No. CTQ2017-90039-R and RTC-2017-6126-1 and the Maria de Maeztu Units of Excellence Program. MDM-2017-0720. The group at Bilbao thank the Agencia Estatal de Investigacion of Spain (Grant RTI2018-094751-B-C21), the European Research Council (RECGLYCANMR, ERC AdG 788143), and the Severo Ochoa Excellence Accreditation SEV-2016-0644. SV acknowledges funding by FRS-FNRS (PDR grant number T.0102.18)., English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1202406840
Document Type :
Electronic Resource