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Carfilzomib Weekly plus Melphalan and Prednisone in Newly Diagnosed Transplant-Ineligible Multiple Myeloma (IFM 2012-03): A Phase I Trial.

Authors :
Leleu, Xavier
Fouquet, Guillemette
Richez, Valentine
Guidez, Stéphanie
Duhamel, Alain
Machuron, François
Karlin, Lionel
Kolb, Brigitte
Tiab, Mourad
Araujo, Carla
Meuleman, Nathalie
Malfuson, Jean Valère
Bourquard, Pascal
Lenain, Pascal
Roussel, Murielle
Jaccard, Arnaud
Pétillon, Marie-Odile
Belhadj-Merzoug, Karim
Lepeu, Gérard
Chrétien, Marie-Lorraine
Fontan, Jean
Rodon, Philippe
Schmitt, Anna
Offner, Fritz
Voillat, Laurent
Cereja, Sophie
Kuhnowski, Frédérique
Rigaudeau, Sophie
Decaux, Olivier
Humbrecht-Kraut, Catherine
Frayfer, Jamile
Fitoussi, Olivier
Roos-Weil, Damien
Eisenmann, Jean Claude
Dorvaux, Véronique
Voog, Eric G
Attal, Michel
Moreau, Philippe
Avet-Loiseau, Herve
Hulin, Cyrille
Facon, Thierry
Leleu, Xavier
Fouquet, Guillemette
Richez, Valentine
Guidez, Stéphanie
Duhamel, Alain
Machuron, François
Karlin, Lionel
Kolb, Brigitte
Tiab, Mourad
Araujo, Carla
Meuleman, Nathalie
Malfuson, Jean Valère
Bourquard, Pascal
Lenain, Pascal
Roussel, Murielle
Jaccard, Arnaud
Pétillon, Marie-Odile
Belhadj-Merzoug, Karim
Lepeu, Gérard
Chrétien, Marie-Lorraine
Fontan, Jean
Rodon, Philippe
Schmitt, Anna
Offner, Fritz
Voillat, Laurent
Cereja, Sophie
Kuhnowski, Frédérique
Rigaudeau, Sophie
Decaux, Olivier
Humbrecht-Kraut, Catherine
Frayfer, Jamile
Fitoussi, Olivier
Roos-Weil, Damien
Eisenmann, Jean Claude
Dorvaux, Véronique
Voog, Eric G
Attal, Michel
Moreau, Philippe
Avet-Loiseau, Herve
Hulin, Cyrille
Facon, Thierry
Source :
Clinical cancer research, 25 (14
Publication Year :
2019

Abstract

Carfilzomib is a novel generation proteasome inhibitor. The Carmysap trial demonstrated that twice-weekly KMP (carfilzomib, melphalan, prednisone) might challenge the MPV (melphalan, prednisone, bortezomib) standard. We sought to study KMP weekly, allowing to increase carfilzomib's dose with maintained efficacy and improved safety profile.<br />SCOPUS: ar.j<br />info:eu-repo/semantics/published

Details

Database :
OAIster
Journal :
Clinical cancer research, 25 (14
Notes :
1 full-text file(s): application/pdf, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1192456022
Document Type :
Electronic Resource