Trunk Skeletal Muscle Mass and Phase Angle Measured by Bioelectrical Impedance Analysis are Associated with the Chance of Femoral Neck Fracture in Very Elderly People

Jia Chen,1,* Kai Lu,2,* Hong Chen,3 Ning Hu,3 Jie Chen,3 Xi Liang,3 Jian Qin,1 Wei Huang3 1Department of Clinical Nutrition, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, People’s Republic of China; 2Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, People’s Republic of China; 3Department of Orthopedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei HuangDepartment of Orthopedic Surgery, The First Affiliated Hospital of Chongqing Medical University, No. 1, Youyi Road, Chongqing 400016, People’s Republic of ChinaTel +86-13883383330Fax +86-23 89011211Email drhuangwei@yeah.netBackground: The study aimed to investigate the potential association of trunk skeletal muscle mass (tSM) and phase angle measured by bioelectrical impedance analysis (BIA) with the chance of femoral neck fractures in very elderly people.Patients and Methods: This case-control study enrolled 78 femoral neck fracture patients aged over 75 years (29 males) and 1:2 matched healthy controls. All participants were subjected to BIA examination by specialists. tSM, the corrected values by height squared of tSM (tSMI) and phase angle were compared between fracture patients and controls. Multivariate logistic regression was performed to explore the strength of association of femoral neck fracture with tSM, tSMI, and phase angle.Results: tSM (kg) of fracture patients was significantly lower than those of controls in all participants (women: 13.49± 0.42 vs 15.44± 0.39, p< 0.05; men: 15.30± 0.71 vs 17.54± 0.78, p< 0.05). In the sarcopenic subgroup, fracture patients also got a lower tSM than controls (women: 12.58± 0.21 vs 13.62± 0.16, p< 0.05; men:14.41&plus