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Functional polymorphisms within the inflammatory pathway regulate expression of extracellular matrix components in a genetic risk dependent model for anterior cruciate ligament injuries

Authors :
Suijkerbuijk, M.A.M. (Mathijs)
Ponzetti, M. (Marco)
Rahim, M. (Masouda)
Posthumus, M. (Michael)
Häger, C.K. (Charlotte K.)
Stattin, E.-L.
Nilsson, K.G. (Kjell G.)
Teti, A. (Anna)
Meuffels, D.E. (Duncan)
Eerden, B.C.J. (Bram) van der
Collins, M. (Malcolm)
September, A.V. (Alison V.)
Suijkerbuijk, M.A.M. (Mathijs)
Ponzetti, M. (Marco)
Rahim, M. (Masouda)
Posthumus, M. (Michael)
Häger, C.K. (Charlotte K.)
Stattin, E.-L.
Nilsson, K.G. (Kjell G.)
Teti, A. (Anna)
Meuffels, D.E. (Duncan)
Eerden, B.C.J. (Bram) van der
Collins, M. (Malcolm)
September, A.V. (Alison V.)
Publication Year :
2019

Abstract

Objectives: To investigate the functional effect of genetic polymorphisms of the inflammatory pathway on structural extracellular matrix components (ECM) and the susceptibility to an anterior cruciate ligament (ACL) injury. Design: Laboratory study, case–control study. Methods: Eight healthy participants were genotyped for interleukin (IL)1B rs16944 C > T and IL6 rs1800795 G > C and c

Details

Database :
OAIster
Notes :
application/pdf, Journal of Science and Medicine in Sport vol. 22 no. 11, pp. 1219-1225, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1157012678
Document Type :
Electronic Resource
Full Text :
https://doi.org/10.1016.j.jsams.2019.07.012