Simultaneous estimation of simvastatin and labetalol in bulk and solid dosage form

A simple, accurate, precise, sensitive, and highly selective ultra violet spectrometer method has been developed for the simultaneous estimation of simvastatin and labetalol in bulk and solid dosage form. The estimation of simvastatin was carried out at 239 nm while labetalol was estimated at 222.4 nm. The developed method was validated for linearity range, precision, recovery studies and interference study for mixture, all these parameter showed the adaptability of the method for the method quality analysis of the drug in bulk and combination formulation. Keywords: Simvastatin, Labetalol, UV Spectrophotometric, Dosage form.