CGHcall: calling aberrations for array CGH tumor profiles

Authors :: van de Wiel, M.A.
Kim, K.I.
Vosse, S.
van Wieringen, W.N.
Wilting, S.M.
Ylstra, B.
van de Wiel, M.A.
Kim, K.I.
Vosse, S.
van Wieringen, W.N.
Wilting, S.M.
Ylstra, B.
Source :: Vrije Universiteit Amsterdam Repository
Publication Year :: 2007
Abstract: Summary: CGHcall achieves high calling accuracy for array CGH data by effective use of breakpoint information from segmentation and by inclusion of several biological concepts that are ignored by existing algorithms. The algorithm is validated for simulated and verified real array CGH data. By incorporating more than three classes, CGHcall improves detection of single copy gains and amplifications. Moreover, it allows effective inclusion of chromosome arm information. © The Author 2007. Published by Oxford University Press. All rights reserved.

Database :: OAIster
Journal :: Vrije Universiteit Amsterdam Repository
Notes :: Bioinformatics vol.23 (2007) nr.7 p.892-894 [ISSN 1367-4803], English
Publication Type :: Electronic Resource
Accession number :: edsoai.on1136595773
Document Type :: Electronic Resource
Full Text :: https://doi.org/10.1093.bioinformatics.btm030