Differential processing of quantity and order of numbers : neuropsychological, electrophysiological and behavioural evidence

Numbers convey different meanings when used in different contexts (Wiese, 2003). In a cardinal context, a number will tell us how many entities are in a set and convey quantity meaning. In an ordinal context, a number will refer to the relative position (or rank) of one element within a sequence; non-numerical ordered series (e.g. the letters of the alphabet) can also be used to provide meaningful order information. Because quantity and order are linked up with each other in the cognitive number domain (the larger the quantity a number refers to, the later it is located in the conventional number sequence), the question of whether they rely on some common or distinct underlying mechanism(s) is theoretically relevant and was addressed in the present thesis. Experimental studies showed evidence of both similarities (similar distance and SNARC effects, recruitment of parietal and frontal regions, and conjoint impairment or preservation after brain damage) and dissociations (different developmental course, dissociation after cerebral lesion, and specific behavioural markers) between quantity and order neuro-functional processes. The aim of the present thesis was to clarify the relationship between numerical quantity and order processing and to test the hypothesis that they rely on (at least partially) dissociated mechanisms. We tested this hypothesis in a single case study, an electrophysiological study and in two behavioural experiments. In the neuropsychological study, we reported the case of patient CO, who showed Gerstmann syndrome after bilateral parietal damage and became unable to process sequence order relations (e.g. he couldn't recite the number sequence backwards, nor decide whether a number, letter, day or month comes before or after a given target in the corresponding sequence, and he was unable to verify the order of items in a pair). Nonetheless, the patient had largely preserved quantity processing abilities (he could compare numbers and dot patterns to
(PSY 3)--UCL, 2005