May gender influence the quality of life in children and adolescents with type 1 diabetes?

Karolina DÅ‚użniak-GoÅ‚aska,1 Dorota Szostak-WÄ™gierek,1 Mariusz Panczyk,2 Agnieszka Szypowska,3 Beata SiÅ„ska4 1Department of Clinical Dietetics, Faculty of Health Sciences, Medical University of Warsaw, Warsaw, Poland; 2Department of Education and Research in Health Sciences, Faculty of Health Sciences, Medical University of Warsaw, Warsaw, Poland; 3Department of Pediatrics, The First Faculty of Medicine, Medical University of Warsaw, Warsaw, Poland; 4Department of Human Nutrition, Faculty of Health Sciences, Medical University of Warsaw, Warsaw, PolandCorrespondence: Mariusz PanczykDepartment of Education and Research in Health Sciences, Faculty of Health Sciences, Medical University of Warsaw, Zwirki i Wigury 61, Warsaw 02-091, PolandTel +48 22 572 0490Fax +48 22 572 0491Email mariusz.panczyk@wum.edu.plIntroduction: Appropriate health-related quality of life (HRQOL) in children and adolescents with type 1 diabetes constitutes one of the most important factors that determine treatment effectiveness. There are numerous studies which tackle the issue of the relationship between HRQOL and various clinical and demographic factors, including gender. Therefore, the aim of the present study was to assess HRQOL and identify factors by which it may be affected, with particular emphasis on gender.Material and methods: The study group included 197 girls and boys (13.9±2.33 years old) with a history of type 1 diabetes (>1 year) treated with the use of insulin pumps. PedsQL Diabetes Module 3.0 questionnaire was used in the assessment of HRQOL. Multivariate linear regression with gender as a covariate was used to investigate the relationship between total PedsQL score and selected variables associated with patient characteristics, insulin dosage and the control of glycemia. Moreover, the presence of gender differences was verified in terms of variables which significantly affected HRQOL.Results: Significantly higher results were observed in boys as regards t