Impact of Age and Comorbidity on Choice and Outcome of Two Different Treatment Options for Patients with Potentially Curable Esophageal Cancer

Authors :: Faiz, Z. (Zohra)
Putten, M. (Margreet) van
Verhoeven, R.H.A. (Rob)
Sandick, J.W. (J.) van
Nieuwenhuijzen, G.A.P.
van der Sangen, M.J.C.
Lemmens, V.E.P.P. (Valery)
Wijnhoven, B.P.L. (Bas)
Plukker, JTM
Faiz, Z. (Zohra)
Putten, M. (Margreet) van
Verhoeven, R.H.A. (Rob)
Sandick, J.W. (J.) van
Nieuwenhuijzen, G.A.P.
van der Sangen, M.J.C.
Lemmens, V.E.P.P. (Valery)
Wijnhoven, B.P.L. (Bas)
Plukker, JTM
Publication Year :: 2019
Abstract: Purpose. This study was designed to assess the impact of age and comorbidity on choice and outcome of definitive chemoradiotherapy (dCRT) or neoadjuvant chemoradiotherapy plus surgery. Methods. In this population-based study, all patients with potentially curable EC (cT1N?/cT2-3, TX, any cN, cM0) diagnosed in the South East of the Netherlands between 2004 and 2014 were included. Kaplan–Meier method with log-rank tests and multivariable Cox regression analysis were used to compare overall survival (OS). Results. A total of 702 patients was included. Age C 75 years and multiple comorbidities were associated with a higher p

Database :: OAIster
Notes :: application/pdf, Annals of Surgical Oncology vol. 26 no. 4, pp. 986-995, English
Publication Type :: Electronic Resource
Accession number :: edsoai.on1111586363
Document Type :: Electronic Resource
Full Text :: https://doi.org/10.1245.s10434-019-07181-6

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