Plasma Cell-Free DNA Testing of Patients With EGFR Mutant Non-Small-Cell Lung Cancer: Droplet Digital PCR Versus Next-Generation Sequencing Compared With Tissue-Based Results

Authors :: Steendam, C.M.J.
Atmodimedjo, P.
Jonge, E. (Evert) de
Paats, M.S. (Marthe)
van der Leest, C
Oomen - de Hoop, E. (Esther)
von der Thusen, JH
Dinjens, W.N.M. (Winand)
Schaik, R.H.N. (Ron) van
Aerts, J.G.J.V. (Joachim)
Dubbink, H.J. (Erik Jan)
Steendam, C.M.J.
Atmodimedjo, P.
Jonge, E. (Evert) de
Paats, M.S. (Marthe)
van der Leest, C
Oomen - de Hoop, E. (Esther)
von der Thusen, JH
Dinjens, W.N.M. (Winand)
Schaik, R.H.N. (Ron) van
Aerts, J.G.J.V. (Joachim)
Dubbink, H.J. (Erik Jan)
Publication Year :: 2019
Abstract: PURPOSE To compare the results of plasma cell-free DNA (cfDNA) droplet digital PCR (ddPCR) and nextgeneration sequencing (NGS) on detection of epidermal growth factor receptor (EGFR) primary activating mutations and p.T790M with results of tissue analysis in patients with EGFR mutated non–small-cell lung

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