Back to Search
Start Over
A short stereoselective synthesis of (+)-aza-galacto-fagomine (AGF)
- Source :
- Tetrahedron
- Publication Year :
- 2017
-
Abstract
- A catalytic asymmetric synthesis of (+)-aza-galacto-fagomine (AGF) - the most promising compound for the pharmacological chaperone therapy of Krabbe disease was accomplished in six steps, in 14% overall yield. The synthesis hinges on the combination of organocatalyzed aldolization and reductive hydrazination.
Details
- Database :
- OAIster
- Journal :
- Tetrahedron
- Notes :
- Tetrahedron
- Publication Type :
- Electronic Resource
- Accession number :
- edsoai.on1111398146
- Document Type :
- Electronic Resource