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How to Assess Drug Resistance in Cancer Stem Cells

Authors :
Gianpaolo Papaccio and Vincenzo Desiderio
De Angelis, Maria Laura
De Maria Marchiano, Ruggero
Marta, Baiocchi
Maria Laura De Angelis
De Maria Marchiano Ruggero (ORCID:0000-0003-2255-0583)
Gianpaolo Papaccio and Vincenzo Desiderio
De Angelis, Maria Laura
De Maria Marchiano, Ruggero
Marta, Baiocchi
Maria Laura De Angelis
De Maria Marchiano Ruggero (ORCID:0000-0003-2255-0583)
Publication Year :
2017

Abstract

Banks of genetically characterized cancer stem cells (CSCs) isolated from individual patients and grown as spheroids offer an invaluable approach to identify genetic determinants of drug resistance versus sensitivity, and to study new stem cell-directed therapies. Here, we describe our standardized procedure for in vitro drug screening on colorectal CSCs, taking irinotecan as an example.

Details

Database :
OAIster
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1105020284
Document Type :
Electronic Resource