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Male fertility and reduction in semen parameters: A single tertiary-care center experience

Authors :
Milardi, Domenico
Grande, Giuseppe
Sacchini, Dario
Astorri, Anna Laura
Pompa, Giuseppina
Giampietro, Antonella
De Marinis, Laura
Pontecorvi, Alfredo
Spagnolo, Antonio Gioacchino
Marana, Riccardo
Sacchini, Dario (ORCID:0000-0002-1581-3018)
De Marinis, Laura (ORCID:0000-0001-9916-0669)
Pontecorvi, Alfredo (ORCID:0000-0003-0570-6865)
Spagnolo, Antonio Gioacchino (ORCID:0000-0002-5762-2164)
Marana, Riccardo (ORCID:0000-0003-1616-7836)
Milardi, Domenico
Grande, Giuseppe
Sacchini, Dario
Astorri, Anna Laura
Pompa, Giuseppina
Giampietro, Antonella
De Marinis, Laura
Pontecorvi, Alfredo
Spagnolo, Antonio Gioacchino
Marana, Riccardo
Sacchini, Dario (ORCID:0000-0002-1581-3018)
De Marinis, Laura (ORCID:0000-0001-9916-0669)
Pontecorvi, Alfredo (ORCID:0000-0003-0570-6865)
Spagnolo, Antonio Gioacchino (ORCID:0000-0002-5762-2164)
Marana, Riccardo (ORCID:0000-0003-1616-7836)
Publication Year :
2012

Abstract

Background. Infertility is both a clinical and a public problem, affecting the life of the couple, the healthcare services, and social environment. Standard semen analysis is the surrogate measure of male fertility in clinical practice. Objective. To provide information about the relationship between semen parameters and spontaneous conception. Methods. We evaluated retrospectively 453 pregnancies that occurred among 2935 infertile couples evaluated at an infertility clinic of a tertiary-care university hospital, between 2004 and 2009. Results. Normal semen analysis was present only in 158 patients; 295 subfertile patients showed alterations in at least one seminal parameter. A reduction in all seminal parameters was observed in 41 patients. Etiological causes of male infertility were identified in 314 patients. Conclusion. Our data highlights the possibility of a spontaneous conception with semen parameters below WHO reference values. Therefore, we support the importance of defining reference values on a population of fertile men. Finally, we analyzed the related ethical issues. Copyright © 2012 D. Milardi et al.

Details

Database :
OAIster
Notes :
English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1105000669
Document Type :
Electronic Resource