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Genome-wide association meta-analysis of coronary artery disease and periodontitis reveals a novel shared risk locus

Authors :
Munz, M. (Matthias)
Richter, G.M. (Gesa M.)
Loos, B.G. (Bruno G.)
Jepsen, S. (Søren)
Divaris, K. (Kimon)
Offenbacher, S. (Steven)
Teumer, A. (Alexander)
Holtfreter, B. (Birte)
Kocher, T. (Thomas)
Bruckmann, C. (Corinna)
Jockel-Schneider, Y. (Yvonne)
Graetz, C. (Christian)
Munoz, L. (Loreto)
Bhandari, A. (Anita)
Tennstedt, S. (Stephanie)
Staufenbiel, I. (Ingmar)
Velde, N. (Nathalie) van der
Uitterlinden, A.G. (André)
de Groot, L.C.P.G.M. (Lisette C. P. G. M.)
Wellmann, J. (Jürgen)
Berger, K. (Klaus)
Krone, B.
Hoffmann, P. (Per)
Laudes, M. (Matthias)
Lieb, W. (Wolfgang)
Franke, A. (Andre)
Dommisch, H. (Henrik)
Erdmann, J. (Jeanette)
Schaefer, A. (Antje)
Munz, M. (Matthias)
Richter, G.M. (Gesa M.)
Loos, B.G. (Bruno G.)
Jepsen, S. (Søren)
Divaris, K. (Kimon)
Offenbacher, S. (Steven)
Teumer, A. (Alexander)
Holtfreter, B. (Birte)
Kocher, T. (Thomas)
Bruckmann, C. (Corinna)
Jockel-Schneider, Y. (Yvonne)
Graetz, C. (Christian)
Munoz, L. (Loreto)
Bhandari, A. (Anita)
Tennstedt, S. (Stephanie)
Staufenbiel, I. (Ingmar)
Velde, N. (Nathalie) van der
Uitterlinden, A.G. (André)
de Groot, L.C.P.G.M. (Lisette C. P. G. M.)
Wellmann, J. (Jürgen)
Berger, K. (Klaus)
Krone, B.
Hoffmann, P. (Per)
Laudes, M. (Matthias)
Lieb, W. (Wolfgang)
Franke, A. (Andre)
Dommisch, H. (Henrik)
Erdmann, J. (Jeanette)
Schaefer, A. (Antje)
Publication Year :
2018

Abstract

Evidence for a shared genetic basis of association between coronary artery disease (CAD) and periodontitis (PD) exists. To explore the joint genetic basis, we performed a GWAS meta-analysis. In the discovery stage, we used a German aggressive periodontitis sample (AgP-Ger; 680 cases vs 3,973 co

Details

Database :
OAIster
Notes :
application/pdf, Scientific Reports vol. 8 no. 1, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1081018380
Document Type :
Electronic Resource
Full Text :
https://doi.org/10.1038.s41598-018-31980-8