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A new approach towards the synthesis of pyrrolo[2,1-a]isoquinolines

Authors :
Voskressensky L.G.
Listratova A.V.
Bolshov A.V.
Bizhko O.V.
Borisova T.N.
Varlamov A.V.
Voskressensky L.G.
Listratova A.V.
Bolshov A.V.
Bizhko O.V.
Borisova T.N.
Varlamov A.V.
Source :
Tetrahedron Letters

Abstract

Reaction of 5-bromo-2-methyl-8-nitro-1,2,3,4-tetrahydroisoquinoline with activated alkynes affords stable tetrahydropyrrolo[2,1-a]isoquinolin-4-ium ylides. Further reactions of ylide 2 gives access to substituted dihydropyrrolo[2,1-a]isoquinolines in good yields. © 2009 Elsevier Ltd. All rights reserved.

Details

Database :
OAIster
Journal :
Tetrahedron Letters
Publication Type :
Electronic Resource
Accession number :
edsoai.on1076912198
Document Type :
Electronic Resource