Back to Search Start Over

Age at first birth in women is genetically associated with increased risk of schizophrenia

Authors :
Ni, G. (Guiyan)
Gratten, J. (Jacob)
Wray, N.R. (Naomi R.)
Lee, S.H. (Sang Hong)
Ripke, S. (Stephan)
Neale, B.M. (Benjamin)
Corvin, A. (Aiden)
Walters, J.T. (James)
Farh, K.-H. (Kai-How)
Holmans, P.A. (Peter A.)
Lee, P.H. (Phil H.)
Bulik-Sullivan, B.K. (Brendan)
Collier, D.A. (David)
Huang, H. (Hailiang)
Pers, T.H. (Tune)
Agartz, I. (Ingrid)
Agerbo, E. (Esben)
Albus, M. (Margot)
Alexander, M. (Madeline)
Amin, F. (Farooq)
Bacanu, S.A. (Silviu)
Begemann, M. (Martin)
Belliveau, R.A. (Richard A.)
Bene, J. (Judit)
Bergen, S.E. (Sarah)
Bevilacqua, E. (Elizabeth)
Bigdeli, T.B. (Tim B.)
Black, D.W. (Donald)
Bruggeman, R. (Richard)
Buccola, N.G. (Nancy G)
Buckner, M.
Byerley, W.F. (William F)
Cahn, W. (Wiepke)
Cai, G. (Guiqing)
Campion, D. (Dominique)
Cantor, R.M.
Carr, V.J. (Vaughan J.)
Carrera, N. (Noa)
Catts, S.V. (Stanley)
Chambert, K. (Kimberly)
Chan, R.C.K. (Raymond C. K.)
Chen, R.Y.L. (Ronald Y.)
Chen, E.Y.H. (Eric Y. H.)
Cheng, W. (Wei)
Cheung, E.F.C. (Eric F. C.)
Chong, S.A. (Siow Ann)
Cloninger, C.R. (C Robert)
Cohen, D.J. (David J.)
Cohen, N. (Nadine)
Cormican, P. (Paul)
Craddock, N.J. (Nick)
Crowley, J.J. (James)
Curtis, D. (David)
Davidson, M.W. (Michael )
Davis, K.L. (Kenneth)
Degenhardt, F.
Del-Favero, J. (Jurgen)
Demontis, D. (Ditte)
Dikeos, D. (Dimitris)
Dinan, T. (Timothy)
Djurovic, S. (Srdjan)
Donohoe, D.J. (Dennis)
Drapeau, E. (Elodie)
Duan, J. (Jubao)
Dudbridge, F. (Frank)
Durmishi, N. (Naser)
Eichhammer, P. (Peter)
Hagen, K. (Knut)
Escott-Price, V. (Valentina)
Essioux, L. (Laurent)
Fanous, A.H. (Ayman H.)
Farrell, M.S. (Martilias)
Frank, J. (Josef)
Franke, L. (Lude)
Freedman, R. (Robert)
Freimer, N.B. (Nelson)
Friedl, M.
Friedman, J.I. (Joseph)
Fromer, M. (Menachem)
Genovese, G. (Giulio)
Georgieva, I. (Irina)
Giegling, I. (Ina)
Giusti-Rodríguez, P. (Paola)
Godard, S. (Stephanie)
Goldstein, J.I. (Jacqueline)
Golimbet, V. (Vera)
Gopal, R. (Robin)
Haan, L. (Lieuwe) de
Hammer, C. (Christian)
Hamshere, M.L. (Marian)
Hansen, M. (Mark)
Hansen, T. (Thomas)
Haroutunian, V. (Vahram)
Hartmann, A.M. (Annette M.)
Henskens, F.A. (Frans)
Herms, S. (Stefan)
Hirschhorn, J.N. (Joel)
Hoffmann, P. (Per)
Hofman, A. (Andrea)
Hollegaard, M.V. (Mads V)
Hougaard, D.M. (David)
Ikeda, M. (Masashi)
Joa, I. (Inge)
Juliá, A. (Antonio)
Kahn, R. (René)
Kalaydjieva, L. (Luba)
Karachanak-Yankova, S. (Sena)
Karjalainen, J. (Juha)
Kavanagh, D. (David)
Keller, M.C. (Matthew C)
Kennedy, J.L.
Khrunin, A. (Andrey)
Kim, Y. (Yunjung)
Klovins, J. (Janis)
Knowles, J.A. (James A)
Konte, B. (Bettina)
Kučinskas, V. (Vaidutis)
Kucinskiene, Z.A. (Zita Ausrele)
Kuzelova-Ptackova, H. (Hana)
Kähler, J. (Jan)
Laurent, C. (Camille)
Keong, J.L.C. (Jimmy Lee Chee)
Legge, S.E. (Sophie)
Lerer, B. (Bernard)
Li, M. (Miaoxin)
Li, T. (Tao)
Liang, K.-Y. (Kung-Yee)
Lieberman, A.P. (Andrew)
Limborska, S. (Svetlana)
Loughland, C.M. (Carmel)
Lubinski, J. (Jan)
Lönnqvist, J. (Jouko)
Macek, M. (Milan MI)
Magnusson, P.K. (Patrik)
Maher, B.S. (Brion)
Maier, W. (Wolfgang)
Mallet, V. (Vincent)
Marsal, S. (Sara)
Mattheisen, M. (Manuel)
Mattingsdal, M. (Morten)
McCarley, R.W. (Robert)
McDonald, C. (Colm)
McIntosh, A.M. (Andrew)
Meier, S.
Meijer, C. (Carin)
Melegh, B. (Bela)
Melle, I. (Ingrid)
Mesholam-Gately, R.I. (Raquelle)
Metspalu, A. (Andres)
Michie, P.T. (Patricia)
Milani, L. (Lili)
Milanova, V. (Vihra)
Mokrab, Y. (Younes)
Morris, D.W. (Derek W.)
Mors, O.
Murphy, K.C. (Kieran)
Murray, R. (Robin)
Myin-Germeys, I. (Inez)
Müller-Myhsok, B. (B.)
Nelis, M. (Mari)
Nenadic, I. (Igor)
Nertney, D.A. (Deborah)
Nestadt, G. (Gerald)
Nicodemus, K.K. (Kristin)
Nikitina-Zake, L. (Liene)
Nisenbaum, L. (Laura)
Nordin, A. (Annelie)
O'Callaghan, E. (Eadbhard)
O'Dushlaine, C. (Colm)
O'neill, F.A. (F. Anthony)
Oh, S.-Y. (Sang-Yun)
Olincy, A. (Ann)
Olsen, L. (Line)
Os, J.V. (Jim Van)
Pantelis, C. (Christos)
Papadimitriou, G.N. (George)
Papiol, S. (Sergi)
Parkhomenko, E. (Elena)
Pato, C. (Carlos)
Paunio, T. (Tiina)
Pejovic-Milovancevic, M. (Milica)
Perkins, D.O. (Diana O.)
Pietiläinen, O.P.H. (Olli)
Pimm, J. (Jonathan)
Pocklington, A.J. (Andrew)
Powell, J. (John)
Price, A. (Alkes)
Pulver, A.E. (Ann)
Purcell, S.M. (Shaun M.)
Quested, D.J. (Digby J)
Rasmussen, H.B. (Henrik B)
Reichenberg, A. (Abraham)
Reimers, B. (Bernhard)
Richards, A. (Alex)
Roffman, J.L. (Joshua)
Roussos, A. (Alexandra)
Ruderfer, D. (Douglas)
Salomaa, V. (Veikko)
Sanders, A.R. (Alan)
Schall, J.D. (Jeffrey)
Schubert, C.R. (Christian R.)
Schulze, T.G. (Thomas)
Schwab, S.G. (Sibylle G.)
Scolnick, E. (Edward)
Scott, R.J. (Rodney J.)
Seidman, L.J. (Larry)
Shi, J. (Jianxin)
Sigurdsson, E. (Engilbert)
Silagadze, T. (Teimuraz)
Silverman, J.M. (Jeremy M.)
Sim, K. (Kang)
Slominsky, P. (Petr)
Smoller, J.W.
So, H.-C. (Hon-Cheong)
Spencer, C.C.A. (Chris C.)
Stahl, E.A. (Eli A.)
Stefansson, H. (Hreinn)
Steinberg, S. (Stacy)
Stogmann, E. (Elisabeth)
Straub, R.E. (Richard)
Strengman, E. (Eric)
Strohmaier, J. (Jana)
Stroup, T.S. (T. Scott)
Subramaniam, V. (Venkat)
Suvisaari, J. (Jaana)
Svrakic, D.M. (Dragan)
Szatkiewicz, J.P. (Jin P.)
Söderman, E. (Erik)
Thirumalai, S. (Srinivasa)
Toncheva, D. (Draga)
Tosato, S. (Sarah)
Veijola, J. (Juha)
Waddington, J. (John)
Walsh, D. (Dermot)
Wang, D. (Dai)
Wang, Q. (Qiang)
Webb, B.T. (Bradley T.)
Weiser, M. (Mark)
Wildenauer, D.B. (Dieter)
Williams, N.M. (Nigel M.)
Williams, S. (Stephanie)
Witt, S.H. (Stephanie H)
Wolen, A.R. (Aaron)
Wong, E.H.M. (Emily H.M.)
Wormley, B.K. (Brandon K.)
Xi, H.S. (Hualin Simon)
Zai, C.C. (Clement C.)
Zheng, X. (Xuebin)
Zimprich, F. (Fritz)
Zwart, J-A. (John-Anker)
Visscher, P.M. (Peter)
Adolfsson, R.
Andreassen, O.A. (Ole)
Blackwood, D.H.R. (Douglas)
Bramon, E. (Elvira)
Buxbaum, J.D. (Joseph D.)
Borglum, A.D. (Anders)
Cichon, S. (Sven)
Darvasi, A. (Ariel)
Domenici, E. (Enrico)
Ehrenreich, H. (Hannelore)
Esko, T. (Tõnu)
Gejman, P.V. (Pablo)
Gill, M. (Michael)
Gurling, H. (Hugh)
Hultman, C.M. (Christina)
Iwata, N. (Nakao)
Jablensky, A. (Assen)
Jönsson, E.G. (Erik)
Kendler, K. (K.)
Kirov, G. (George)
Knight, J. (Jo)
Lencz, T. (Todd)
Levinson, D.F. (Douglas F.)
Li, Q.S. (Qingqin S.)
Liu, J. (Jianjun)
Malhotra, A.K. (Anil K)
McCarroll, S.A. (Steve)
McQuillin, A. (Andrew)
Moran, J.L. (Jennifer L.)
Mortensen, P.B.
Mowry, B.J. (Bryan J)
Nöthen, M.M. (Markus)
Ophoff, R.A. (Roel)
Owen, M.J. (Michael)
Palotie, A. (Aarno)
Petryshen, T.L. (Tracey L.)
Posthuma, D. (Danielle)
Rietschel, M. (Marcella)
Riley, B.P. (Brien P.)
Rujescu, D. (Dan)
Sham, P.C. (Pak C.)
Sklar, P. (Pamela)
Clair, D.S.
Weinberger, D.R. (Daniel)
Wendland, A. (Annika)
Werge, T.M. (Thomas)
Daly, M.J. (Mark J.)
Sullivan, P.F. (Patrick)
O'donovan, M.C. (Michael)
Ni, G. (Guiyan)
Gratten, J. (Jacob)
Wray, N.R. (Naomi R.)
Lee, S.H. (Sang Hong)
Ripke, S. (Stephan)
Neale, B.M. (Benjamin)
Corvin, A. (Aiden)
Walters, J.T. (James)
Farh, K.-H. (Kai-How)
Holmans, P.A. (Peter A.)
Lee, P.H. (Phil H.)
Bulik-Sullivan, B.K. (Brendan)
Collier, D.A. (David)
Huang, H. (Hailiang)
Pers, T.H. (Tune)
Agartz, I. (Ingrid)
Agerbo, E. (Esben)
Albus, M. (Margot)
Alexander, M. (Madeline)
Amin, F. (Farooq)
Bacanu, S.A. (Silviu)
Begemann, M. (Martin)
Belliveau, R.A. (Richard A.)
Bene, J. (Judit)
Bergen, S.E. (Sarah)
Bevilacqua, E. (Elizabeth)
Bigdeli, T.B. (Tim B.)
Black, D.W. (Donald)
Bruggeman, R. (Richard)
Buccola, N.G. (Nancy G)
Buckner, M.
Byerley, W.F. (William F)
Cahn, W. (Wiepke)
Cai, G. (Guiqing)
Campion, D. (Dominique)
Cantor, R.M.
Carr, V.J. (Vaughan J.)
Carrera, N. (Noa)
Catts, S.V. (Stanley)
Chambert, K. (Kimberly)
Chan, R.C.K. (Raymond C. K.)
Chen, R.Y.L. (Ronald Y.)
Chen, E.Y.H. (Eric Y. H.)
Cheng, W. (Wei)
Cheung, E.F.C. (Eric F. C.)
Chong, S.A. (Siow Ann)
Cloninger, C.R. (C Robert)
Cohen, D.J. (David J.)
Cohen, N. (Nadine)
Cormican, P. (Paul)
Craddock, N.J. (Nick)
Crowley, J.J. (James)
Curtis, D. (David)
Davidson, M.W. (Michael )
Davis, K.L. (Kenneth)
Degenhardt, F.
Del-Favero, J. (Jurgen)
Demontis, D. (Ditte)
Dikeos, D. (Dimitris)
Dinan, T. (Timothy)
Djurovic, S. (Srdjan)
Donohoe, D.J. (Dennis)
Drapeau, E. (Elodie)
Duan, J. (Jubao)
Dudbridge, F. (Frank)
Durmishi, N. (Naser)
Eichhammer, P. (Peter)
Hagen, K. (Knut)
Escott-Price, V. (Valentina)
Essioux, L. (Laurent)
Fanous, A.H. (Ayman H.)
Farrell, M.S. (Martilias)
Frank, J. (Josef)
Franke, L. (Lude)
Freedman, R. (Robert)
Freimer, N.B. (Nelson)
Friedl, M.
Friedman, J.I. (Joseph)
Fromer, M. (Menachem)
Genovese, G. (Giulio)
Georgieva, I. (Irina)
Giegling, I. (Ina)
Giusti-Rodríguez, P. (Paola)
Godard, S. (Stephanie)
Goldstein, J.I. (Jacqueline)
Golimbet, V. (Vera)
Gopal, R. (Robin)
Haan, L. (Lieuwe) de
Hammer, C. (Christian)
Hamshere, M.L. (Marian)
Hansen, M. (Mark)
Hansen, T. (Thomas)
Haroutunian, V. (Vahram)
Hartmann, A.M. (Annette M.)
Henskens, F.A. (Frans)
Herms, S. (Stefan)
Hirschhorn, J.N. (Joel)
Hoffmann, P. (Per)
Hofman, A. (Andrea)
Hollegaard, M.V. (Mads V)
Hougaard, D.M. (David)
Ikeda, M. (Masashi)
Joa, I. (Inge)
Juliá, A. (Antonio)
Kahn, R. (René)
Kalaydjieva, L. (Luba)
Karachanak-Yankova, S. (Sena)
Karjalainen, J. (Juha)
Kavanagh, D. (David)
Keller, M.C. (Matthew C)
Kennedy, J.L.
Khrunin, A. (Andrey)
Kim, Y. (Yunjung)
Klovins, J. (Janis)
Knowles, J.A. (James A)
Konte, B. (Bettina)
Kučinskas, V. (Vaidutis)
Kucinskiene, Z.A. (Zita Ausrele)
Kuzelova-Ptackova, H. (Hana)
Kähler, J. (Jan)
Laurent, C. (Camille)
Keong, J.L.C. (Jimmy Lee Chee)
Legge, S.E. (Sophie)
Lerer, B. (Bernard)
Li, M. (Miaoxin)
Li, T. (Tao)
Liang, K.-Y. (Kung-Yee)
Lieberman, A.P. (Andrew)
Limborska, S. (Svetlana)
Loughland, C.M. (Carmel)
Lubinski, J. (Jan)
Lönnqvist, J. (Jouko)
Macek, M. (Milan MI)
Magnusson, P.K. (Patrik)
Maher, B.S. (Brion)
Maier, W. (Wolfgang)
Mallet, V. (Vincent)
Marsal, S. (Sara)
Mattheisen, M. (Manuel)
Mattingsdal, M. (Morten)
McCarley, R.W. (Robert)
McDonald, C. (Colm)
McIntosh, A.M. (Andrew)
Meier, S.
Meijer, C. (Carin)
Melegh, B. (Bela)
Melle, I. (Ingrid)
Mesholam-Gately, R.I. (Raquelle)
Metspalu, A. (Andres)
Michie, P.T. (Patricia)
Milani, L. (Lili)
Milanova, V. (Vihra)
Mokrab, Y. (Younes)
Morris, D.W. (Derek W.)
Mors, O.
Murphy, K.C. (Kieran)
Murray, R. (Robin)
Myin-Germeys, I. (Inez)
Müller-Myhsok, B. (B.)
Nelis, M. (Mari)
Nenadic, I. (Igor)
Nertney, D.A. (Deborah)
Nestadt, G. (Gerald)
Nicodemus, K.K. (Kristin)
Nikitina-Zake, L. (Liene)
Nisenbaum, L. (Laura)
Nordin, A. (Annelie)
O'Callaghan, E. (Eadbhard)
O'Dushlaine, C. (Colm)
O'neill, F.A. (F. Anthony)
Oh, S.-Y. (Sang-Yun)
Olincy, A. (Ann)
Olsen, L. (Line)
Os, J.V. (Jim Van)
Pantelis, C. (Christos)
Papadimitriou, G.N. (George)
Papiol, S. (Sergi)
Parkhomenko, E. (Elena)
Pato, C. (Carlos)
Paunio, T. (Tiina)
Pejovic-Milovancevic, M. (Milica)
Perkins, D.O. (Diana O.)
Pietiläinen, O.P.H. (Olli)
Pimm, J. (Jonathan)
Pocklington, A.J. (Andrew)
Powell, J. (John)
Price, A. (Alkes)
Pulver, A.E. (Ann)
Purcell, S.M. (Shaun M.)
Quested, D.J. (Digby J)
Rasmussen, H.B. (Henrik B)
Reichenberg, A. (Abraham)
Reimers, B. (Bernhard)
Richards, A. (Alex)
Roffman, J.L. (Joshua)
Roussos, A. (Alexandra)
Ruderfer, D. (Douglas)
Salomaa, V. (Veikko)
Sanders, A.R. (Alan)
Schall, J.D. (Jeffrey)
Schubert, C.R. (Christian R.)
Schulze, T.G. (Thomas)
Schwab, S.G. (Sibylle G.)
Scolnick, E. (Edward)
Scott, R.J. (Rodney J.)
Seidman, L.J. (Larry)
Shi, J. (Jianxin)
Sigurdsson, E. (Engilbert)
Silagadze, T. (Teimuraz)
Silverman, J.M. (Jeremy M.)
Sim, K. (Kang)
Slominsky, P. (Petr)
Smoller, J.W.
So, H.-C. (Hon-Cheong)
Spencer, C.C.A. (Chris C.)
Stahl, E.A. (Eli A.)
Stefansson, H. (Hreinn)
Steinberg, S. (Stacy)
Stogmann, E. (Elisabeth)
Straub, R.E. (Richard)
Strengman, E. (Eric)
Strohmaier, J. (Jana)
Stroup, T.S. (T. Scott)
Subramaniam, V. (Venkat)
Suvisaari, J. (Jaana)
Svrakic, D.M. (Dragan)
Szatkiewicz, J.P. (Jin P.)
Söderman, E. (Erik)
Thirumalai, S. (Srinivasa)
Toncheva, D. (Draga)
Tosato, S. (Sarah)
Veijola, J. (Juha)
Waddington, J. (John)
Walsh, D. (Dermot)
Wang, D. (Dai)
Wang, Q. (Qiang)
Webb, B.T. (Bradley T.)
Weiser, M. (Mark)
Wildenauer, D.B. (Dieter)
Williams, N.M. (Nigel M.)
Williams, S. (Stephanie)
Witt, S.H. (Stephanie H)
Wolen, A.R. (Aaron)
Wong, E.H.M. (Emily H.M.)
Wormley, B.K. (Brandon K.)
Xi, H.S. (Hualin Simon)
Zai, C.C. (Clement C.)
Zheng, X. (Xuebin)
Zimprich, F. (Fritz)
Zwart, J-A. (John-Anker)
Visscher, P.M. (Peter)
Adolfsson, R.
Andreassen, O.A. (Ole)
Blackwood, D.H.R. (Douglas)
Bramon, E. (Elvira)
Buxbaum, J.D. (Joseph D.)
Borglum, A.D. (Anders)
Cichon, S. (Sven)
Darvasi, A. (Ariel)
Domenici, E. (Enrico)
Ehrenreich, H. (Hannelore)
Esko, T. (Tõnu)
Gejman, P.V. (Pablo)
Gill, M. (Michael)
Gurling, H. (Hugh)
Hultman, C.M. (Christina)
Iwata, N. (Nakao)
Jablensky, A. (Assen)
Jönsson, E.G. (Erik)
Kendler, K. (K.)
Kirov, G. (George)
Knight, J. (Jo)
Lencz, T. (Todd)
Levinson, D.F. (Douglas F.)
Li, Q.S. (Qingqin S.)
Liu, J. (Jianjun)
Malhotra, A.K. (Anil K)
McCarroll, S.A. (Steve)
McQuillin, A. (Andrew)
Moran, J.L. (Jennifer L.)
Mortensen, P.B.
Mowry, B.J. (Bryan J)
Nöthen, M.M. (Markus)
Ophoff, R.A. (Roel)
Owen, M.J. (Michael)
Palotie, A. (Aarno)
Petryshen, T.L. (Tracey L.)
Posthuma, D. (Danielle)
Rietschel, M. (Marcella)
Riley, B.P. (Brien P.)
Rujescu, D. (Dan)
Sham, P.C. (Pak C.)
Sklar, P. (Pamela)
Clair, D.S.
Weinberger, D.R. (Daniel)
Wendland, A. (Annika)
Werge, T.M. (Thomas)
Daly, M.J. (Mark J.)
Sullivan, P.F. (Patrick)
O'donovan, M.C. (Michael)
Publication Year :
2018

Abstract

Previous studies have shown an increased risk for mental health problems in children born to both younger and older parents compared to children of average-aged parents. We previously used a novel design to reveal a latent mechanism of genetic association between schizophrenia and age at first birth in women (AFB). Here, we use independent data from the UK Biobank (N = 38,892) to replicate the finding of an association between predicted genetic risk of schizophrenia and AFB in women, and to estimate the genetic correlation between schizophrenia

Details

Database :
OAIster
Notes :
application/pdf, Scientific Reports vol. 8 no. 1, English
Publication Type :
Electronic Resource
Accession number :
edsoai.on1047726706
Document Type :
Electronic Resource
Full Text :
https://doi.org/10.1038.s41598-018-28160-z